Eric TopolEvery podcast appearance, updated as new ones drop

Interview: Dr Eric Topol (Part 2) In the second half of our conversation, Dr Eric Topol discusses AI’s promise in reducing clinician burnout, forecasting disease, and reshaping prevention. He also reflects on 13 years since The Creative Destruction of Medicine , shares his favourite transformative tools, and offers advice for clinicians seeking creative careers Australian CDC – the data angle Australia is finally moving ahead with its own Centre for Disease Control, promising better national coordination and public health data sharing. But will it deliver transparency and timely insights—or just more bureaucracy? AI & Fertility – SpermSearchAI delivers first UAE pregnancy An AI tool developed in Australia, by NeoGenix Biosciences, has achieved its first pregnancy in the UAE. The technology speeds up and improves IVF outcomes, showing how Australian health innovation is going global. US Information Blocking Enforcement The US Department of Health and Human Services will finally enforce penalties for health providers and IT vendors who block patient access to their own records. A big step for patient rights, and a reminder of how far Australia still has to go. Apple’s Health Tech Push Apple’s new Watch Series 11 now measures blood pressure and the latest AirPods can track heart rate. These updates blur the line between wellness gadgets and medical devices, raising big questions about accuracy, equity, and data overload. Eli Lilly’s AI Drug Discovery Giveaway Pharma giant Eli Lilly is making its drug discovery language models publicly available through “Lilly TuneLab.” It’s part open-science, part strategic play—accelerating research while still funnelling insights back to Lilly. Australian Robotics – Abi the Care Robot Melbourne startup Andromeda has raised $23m to scale Abi, a friendly robot designed for aged care and children’s hospitals. Founder Grace Brown, just 25, has quickly become one of Australia’s standout young innovators. Resources: Dr Eric Topol’s book SuperAgers Link Dr Eric Topol’s podcast & substack Ground Truths Link Medicine and the Machine podcast with Dr Abraham Verghese and Dr Eric Topol Link Book recommendation: The AI Valley, Gary Rivlin Link Recommended FREE course: AI in Healthcare from RCSI Link Recommended FREE course: Patient Insights Masterclass by Savvy Corporate Link Visit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news. Follow us on LinkedIn Louise | George | Pulse+IT Follow us on BlueSky Louise | George | Pulse+IT Send us your questions pulsepod@p

This episode is brought to you by One Skin and Momentous . Cardiovascular disease remains the leading cause of death worldwide. But today, we no longer have to wait for symptoms to understand our risk. Advances in technology now make it possible to get a clear snapshot of individual risk, not only for heart disease, but also for cancer and neurodegenerative conditions, empowering us to take proactive steps to lower risk and support long-term health. Our guest today breaks down what’s truly worth investing in and what we can skip. Today on The Dhru Purohit Show , Dhru sits down with Dr. Eric Topol, a cardiologist and Professor of Molecular Medicine at the Scripps Research Institute. Dr. Topol shares insights on the importance of preventive health, with a focus on cardiovascular disease, cancer, and neurodegenerative conditions. He explains the role of polygenic risk scores in assessing individual risk, explores the strengths and limitations of various testing methods, and highlights how lifestyle choices shape disease prevention. Dhru and Dr. Topol also discuss emerging technologies in health monitoring, the influence of environmental factors like air pollution, and what the future may hold for aging and health management. Dr. Eric Topol is Executive Vice President and Professor of Molecular Medicine at Scripps Research and founder of the Scripps Research Translational Institute. A practicing cardiologist and one of the ten most-cited researchers in medicine, he is renowned for his wor in AI, genomics, and digital clinical trials. Named to the Time 100 Health list in 2024, he also writes the Ground Truths newsletter and is the author of The Creative Destruction of Medicine , The Patient Will See You Now , Deep Medicine , and Super Agers . In this episode, Dhru and Dr. Topol dive into: Cardiovascular disease causes, risks, and prevention (1:07) Polygenic risk genetic links to disease and understanding your risk (7:56) Heart health with Dr. Topol’s key recommendations (13:21) Cancer testing types of tests and how to approach results (27:47) Medical guidance mistrust, confusion, incidental findings, and the importance of evidence-based practitioners (34:20) Alzheimer’s detection, blood work, testing, and the role of AI (43:13) Environmental risks, air pollution, and sleep irregularity, and why these factors must be addressed (53:20) Parkinson’s disease: the fastest-growing neurodegenerative condition (57:01) Prevention and lowering your risk of developing major diseases (59:52) Gut health and the gut-hormone connection (1:02:05) Aging and immunity: links between age-related diseases and the immune system (1:06:19) Measuring biological age (1:08:14) Final thoughts and takeaways (1:16:27) Also mentioned in this episode: Super Agers: An Evidence-Based Approach to Longevity Polygenic Risk Scores: Ready for Prime Time? What a Polygenic Risk Score Can and Can’t Tell You Allelica Polygenic Risk Test Dhru’s APOE Chat GPT Results <

Interview: Dr Eric Topol (Part 1) We’re joined by Dr Eric Topol—cardiologist, scientist, author, and global digital health leader. In part one, Eric shares his journey from clinician to digital health pioneer, his vision for “SuperAgers,” and why genomics and personalised medicine could redefine how long—and how well—we live Chatbots for Patients We discuss the Wall Street Journal’s bold claim that chatbots could become part of the medical team. From spotting errors to translating lab results and reminding patients about medications, can they really serve as low-risk, always-on companion? Questions remain around accuracy, empathy, and whether they truly add value or just more noise. The Human Side of Interoperability Inspired by Amy Gleason’s LA Times op-ed, we look at the personal impact of fragmented health systems. Her daughter’s care journey shows how disconnected records hinder outcomes—and how AI uncovered a hidden opportunity. Should we lean into more personal stories to communicate to a wider audience? Meta & Who Owns Your Health Data? A San Francisco jury found Meta guilty of illegally harvesting data from millions of Flo app users—menstrual cycles, ovulation, even pregnancy intentions. The ruling highlights urgent questions: Who really owns health data, and what rights do patients have when tech giants treat it like ad fuel? Patient Consent in the Age of AI Consent forms are broken—static, outdated, and unfit for the AI era. We unpack Y. Tony Yang’s American Journal of Bioethics piece arguing for “dynamic consent,” accountability frameworks, and real patient understanding. Without rethinking consent, healthcare risks losing trust as AI tools grow more influential Black Box for Aged Care What if aged care had a “black box,” like aviation? Sensors, AI, and monitoring systems could flag risks before crises hit. A Pulse+IT blog argues for shifting from reactive to proactive care, but business models and adoption lag behind. We debate whether the sector can finally move from inquiry to prevention Resources: Louise’s LinkedIn poll on gen AI use for health research Link Dr Eric Topol’s book SuperAgers Link Y. Tony Yang’s American Journal of Bioethics Article on Patient Consent Link Aged Care’s Black Box in Pulse+IT Link Amy Gleason’s parental perspective on the need for health data interoperability Link Visit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news.

Gil and Eric discuss Eric’s book, Super Agers, and the inspiration behind it: a 98-year-old patient who exemplified healthy aging. They explore the five dimensions of healthspan optimization: lifestyle, omics, the immune system, and the role of data and AI in personalized medicine. Eric highlights how AI can analyze multi-layered data to provide personalized recommendations for preventing age-related diseases. The conversation also explores the importance of exercise, sleep, and social connection for healthy aging, as well as the risks associated with high-dose statins. Eric emphasizes the need for a shift towards preventative care, using data and AI to identify and address individual risks. He stresses the power of lifestyle changes, rather than supplements, in improving long-term health outcomes. Guest-at-a-Glance 💡 Name: Dr. Eric Topol 💡 What they do: Founder and Director 💡 Company: Scripps Research Translational Institute 💡 Noteworthy: Genomics pioneer, digital medicine innovator, and preventative care advocate Episode highlights: [00:00] The Impact of Social Isolation on Health [01:19] Meet Dr. Eric Topol: A Pioneer in Medicine [03:16] Dr. Topol's Personal Journey into Medicine [05:31] The Early Days of Genetic Therapy [07:54] Insights from Dr. Topol's Book: Super Agile [13:02] The Role of Genetics in Longevity [14:22] The Five Dimensions of Healthspan [20:08] The Power of Exercise and Diet [23:58] The Truth About Supplements [32:38] The Importance of Sleep [36:07] The Value of Social Relationships [38:02] The Benefits of Nature and Social Interaction [39:17] Exploring Longevity Drugs: Metformin and Rapamycin [40:10] Risks and Benefits of Longevity Treatments [41:56] The Potential of GLP-1 Drugs [46:41] Statins and Their Impact on Health [51:11] Emerging Cancer Detection Technologies [56:15] The Role of AI and Polygenic Scores in Healthcare [57:36] Preventing Alzheimer's Disease [01:01:14] The Future of Longevity and Healthspan We Appreciate You! As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: https://info.insidetracker.com/podcast For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

João Bocas - The #Wearables Expert ™ Interviews Dr. Eric Topol, World renowned Cardiologist, Digital Health Influencer, Physician - Scientist and Author This is a very special episode that marks the 2 year anniversary of the YouTube Channel. The Topic is: Taking the pulse on Digital Health We've discussed and touched upon : - Digital Health and the state of the industry right now - How the pandemic impacted digital health - Detect Health Study ( using wearables ) Recommended books by Dr. Eric Tol : 1) The Creative Destruction of Medicine 2) The Patient will see you now 3) Deep Medicine BUY HERE - https://drerictopol.com/books/ Share this episode with your networks: https://youtu.be/TVjUlcLVVEM Connect with Dr. Eric Topol : Twitter - https://twitter.com/EricTopol LinkedIn - https://www.linkedin.com/in/eric-topol-md-b83a7317/ Website - https://drerictopol.com/ Feel free to 📣 CONNECT WITH ME 🟢: LinkedIn: https://www.linkedin.com/in/joaobocas/ Twitter: https://twitter.com/WearablesExpert How do you see the state of the industry digital Health right now? It moves very slowly, we've been ready to see a roll out for well over a decade and we have seen some progress obviously the pandemic helped user in Telehealth which is one component but there's so much more especially now that we have the tools of AI to help bring these into the real practice. There's been some progress we still don't have the regard for sensors that I would hope we would broad use of sensors we're still not liberating from keyboard for clinicians. We've made very little progress towards hospital at home which should be attainable, there's many things we can do that we haven't done yet, I would still say we're in the first inning of the digital Health progress and we're still largely an analog entity unfortunately. I do agree with you everything moves really slow unfortunately and we are at the very beginning of this emerging industry. I think it's the most exciting time in medicine and particularly in digital medicine mainly because of deep neural networks The Sweet Spot for AI we're seeing some extraordinary things that are going to change the face of medicine since as you know we rely on scans and images in medicine to a large degree and this will help accuracy but also will provide new information that previously was unattainable and that I think is is really efficient and exciting brilliant We need to use Ai and digital to restore the patient doctor relationship that premise to me is most important as a physician now. For over three decades and as a patient all of us our patients will be patients we've seen marked erosion of that relationship and we need to get it back and the way we get it back the biggest step is the gift of time. The gift of time which is means that we are have more time with patients to listen to hear their stories and concerns to do a careful exam which should include digital tools. I didn't even mention you know smartphone ultrasound which to me is should be part of every physical exam particularly for me it's the smartphone Echo but um also the the rest restoration of trust and presence and empathy all these things have taken a hit in decades since I first became a physician If you have not subscribed, do it now - https://bit.ly/3iQ6EXP#digitalhealth #medicine #healthcare #wearables #digitalhealth #digitalhealthcare #Ai #artificialintelligence

Meet Dr. Eric Topol: Dr. Eric Topol is a cardiologist, scientist, and author. He is the Founder and Director of Scripps Research Translational Institute, and the Executive Vice-President of Scripps Research. He has published over 1200 peer-reviewed articles and is one of the top 10 most cited researchers in medicine. In 2016, Dr. Topol received a $207 million grant from the NIH to lead a portion of All of Us, part of the Precision Medicine Initiative. He is the author of three books on healthcare and is known for his commentary on patient-centered care and artificial intelligence. Key Insights: Dr. Eric Topol is an expert in healthcare personalization and has gained traction on social media for his commentary on COVID-19. Our discussion covers a variety of pandemic response topics, and broadens to the applications of artificial intelligence in the future of healthcare. COVID-19 Response. We discuss testing (13:55), breakthrough cases (16:41), mix and match vaccinations (20:21), hybrid immunity (23:22) and more about COVID-19. Institutional Trust. The pandemic has decreased trust in some government agencies, Dr. Topol describes how it can be won back. (27:10) Artificial Intelligence. Dr. Topol dives into the application of artificial intelligence and deep learning in the future of healthcare. (31:31) Democratization of Medicine. Patients yearn for more control over their care and health data, and are the future of healthcare innovation. (42:11)

A lot has been said about the application of Artificial Intelligence (AI) to healthcare. These discussions typically center on AI’s ability to improve diagnostic accuracy, reduce medical errors, lower healthcare costs, enhance productivity, and even replace providers. We will cover some of that ground as well, but our guest’s perspective takes the discussion far beyond those more familiar topics. His firm belief is that the major impact AI could have on healthcare delivery would be to restore “the human bond, the human touch, and the human factor that has been lost.” This is a unique opinion, but not surprising, given the source. Dr. Eric Topol is a leading global authority on Precision & Personalized Medicine. He is also one of the most outspoken physicians I’ve ever encountered on the issue of patient advocacy, and in his own words, “patient activism.” Dr. Topol is the Founder and Director of the Scripps Research Translational Institute. Prior to assuming his leadership role at Scripps in 2007, he led the Cleveland Clinic to become the #1 center for heart care in the country. He is a nationally renowned cardiologist and literally a superstar in the world of academic Medicine, being one of the top ten most cited medical researchers. He has been elected to the National Academy of Medicine and was voted the #1 most influential physician leader in the United States by Modern Healthcare. In 2016, Dr. Topol was awarded a $207M grant from the NIH to lead a significant part of the Precision Medicine (All of Us) Initiative - one of the largest NIH grants ever awarded. As if all of this wasn’t enough, he has published 2 bestseller books on the future of medicine: The Creative Destruction of Medicine & The Patient Will See You Now . His most recent book, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again , was published this year. The issues we’ll cover in this interview include: Dr. Topol’s perspective on the “shallow medicine” being practiced today and how it harms patients as well as providers. The various applications of AI to healthcare, and Dr. Topol’s take on the most mature and proven applications of AI in Medicine today. The most significant benefit of Artificial Intelligence in healthcare - “the gift of time” and how it can revitalize and rehumanize medical care - for both patients and providers. The challenges, hurdles, and risks we face in further developing and deploying AI-enabled healthcare. Dr. Topol’s refreshing perspective on the characteristics of the ideal medical student, and the relational characteristics we should encourage and support in healthcare providers. What you’ll come away with from this interview is an understanding of how Artificial Intelligence has the potential to elevate the profession of Medicine - not just through the enhancement of diagnostic accuracy, reduction of errors, lowering of costs and a literal leapfrog in efficiency. But, more importantly, through its ability to free up providers’ time and attention, so they can focus on being empathetic experts, guides & teachers. It is this that will restore the human bond that is so sought after in healthcare delivery today. Dr. Topol is keen to point out that this is as much a “gift” to providers as it is to patients. If you listen carefully, you’ll also hear Dr. Topols ‘call-to-action’. He urges us all to become “patient activists” because the future of healthcare is by no means a certain or secure one. He believes that we collectively have the ability, and the responsibility, to assure that the future of healthcare is a hopeful and healing one. I read Dr. Topol’s book, Deep Medicine , and I would urge you t

AI has already made its way into in the medical field, and today, Dr. Eric Topol gives us a sense of the many ways in which medical professionals are already taking advantage of this technology. Dr. Topol is a cardiologist and the author of Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again . He acknowledges AI’s security risks, but is optimistic for the future of health that AI is helping to usher in. Show notes Conversation with Dr. Topol (0:50) Dr. Eric Topol is a cardiologist . Dr. Topol is the founder and director of the Scripps Research Translational Institute . You can find Dr. Topol’s book here: Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again . We want to hear from you. Please send us your comments, suggested topics, and listener questions for future All Turtles Podcast episodes. Email: hello@all-turtles.com Twitter: @allturtlesco

Today's guest: Eric Topol, MD | Founder and Director, Scripps Research Translational Institute Greg and Eric talk about the genesis of Scripps' remarkable efforts in genomics and digital health, the wealth of insight that's already available today due to a wealth of data & advanced "Deep Medicine" and talk about the future impact of Food as Medicine - e.g., "Deep Diet." Important Links: Deep Medicine site: https://drerictopol.com/book/deep-medicine/ Eric Topol's site: https://drerictopol.com/ Eric Topol's Twitter: https://twitter.com/erictopol Escaping the Scarcity Loop by Rupal Shah and John Launer: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31556-9/fulltext The Scripps Institute Transitional Research site: https://www.scripps.edu/science-and-medicine/translational-institute/ "All of Us" Precision Medicine Initiative: https://allofus.nih.gov/ Learn more about your ad choices. Visit megaphone.fm/adchoices

The way we practice medicine today is broken. We prioritize the business and treat the patient as nothing more than a cog in our great machine. According to today’s guest, ” we have an emotional breakdown, with disenchanted patients largely disconnected from burned-out, depressed doctors.” Dr. Eric Topol calls this epidemic “shallow medicine”. It’s driven by runaway healthcare costs and an insatiable drive for increased efficiency and profits, and unfortunately, is largely the way we deliver healthcare today. Because of this, Topol says, “patients exist in a world of insufficient data, insufficient time, insufficient context, and insufficient presence.” But, Dr. Topol is optimistic. He believes that Artificial Intelligence (AI), while still finding its place in medicine, and still mostly unproven in real-world clinical situations, can create the space we need to change course. In his new book, Deep Medicine, Dr. Topol makes an optimistic, but realistic argument for how artificial intelligence can make healthcare human again. He tells us that it’s early, and this is definitely a race with no finish line, but we’ve seen great progress so far and there’s plenty of evidence that the tools will have a profound impact on every part of healthcare. Dr. Topol believes that we will get there, and that AI will create new efficiencies and workflows that can be used to either make things really good, or really bad. He tells us that “the increased efficiency and workflow could either be used to squeeze clinicians more, or the gift of time could be turned back to patients – to use the future to bring back the past.” On this episode, Dr. Topol explains his thesis and we explore the potential paths from where we are now, to where we might go. Dr. Topol makes a compelling case for breaking that inertia and putting the priority back on the patient. For full show notes, link and bios, visit https://thehcbiz.com/deep-medicine-eric-topol/