Eric TopolEvery podcast appearance, updated as new ones drop

In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Eric Topol, MD, move from the science of aging to how to think about AI-enabled medicine. Topol discusses what it will take for AI to move medicine from reactive to predictive, why some well-validated imaging AI remains underused while large language models have spread rapidly, and whether AI is actually giving clinicians more time with patients. Related Content: From Aging to AI and Beyond

We all want to live longer, healthier lives. But right now, there’s more noise than ever about how to do it. That’s where trusted voices matter, especially those working at the intersection of research, innovation and clinical practice. In this episode of the Best Leaders Podcast from U.S. News & World Report, Eric Gertler, Executive Chairman and CEO of U.S. News, and Arun Gupta, CEO of the NobleReach Foundation, speak with Eric Topol, M.D., Professor and Executive Vice President at Scripps Research and Founder and Director of the Scripps Research Translational Institute. Topol is a practicing cardiologist and one of the top 10 most cited researchers in medicine, with more than 1,300 peer-reviewed papers and clinical trials in more than 40 countries. His 2025 book, “Super Agers,” makes the evidence-based case for extending not just lifespan, but health span – the years we are actually healthy. But what earned Topol a place on the U.S. News Best Leaders list is not just his scientific achievements. It is his commitment to living by his motto: “Think big. Act bigger.” Learn more: U.S. News Best Leaders: https://www.usnews.com/news/best-leaders Eric Topol’s U.S. News Best Leaders profile: https://www.usnews.com/news/leaders/articles/best-leaders-2025-eric-topol Eric Topol’s book, “Super Agers”: https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666 More from U.S. News & World Report: https://www.usnews.com/

Dr. Eric Topol, the founder and director of the Scripps Research Translational Institute, joins Kara to discuss reality versus the hype in the booming longevity business ahead of her new CNN series "Kara Swisher Wants to Live Forever."  Dr. Topol has written several books, including his latest, "Super Agers: An Evidence-Based Approach to Longevity," which explores the science behind anti-aging and longevity. He explains why the biggest breakthroughs in aging science focus not on extending lifespan, but on extending health span and preventing the chronic diseases that affect most Americans over 65. And Topol takes aim at the “longevity lifespan circus” of pricey supplements and peptides sold by wellness grifters. Kara and Dr. Topol also talk about how inequality, poverty and the lack of universal healthcare in the US impact health span, and what can be done about it.  Questions? Comments? Email us at on@voxmedia.com or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this episode of The Future of Medicine, we welcome Eric Topol, MD, cardiologist, scientist, bestselling author of Super Agers, and founder of the Scripps Research Translational Institute, whose work has helped shape the field of digital medicine and the use of data, genomics, and artificial intelligence to personalize care. Dr. Topol reflects on how medicine is shifting from treating disease to preventing it, and why extending health span—the years we live in good health—may be one of the most important goals in modern science. He explains how advances in biomarkers, wearable technology, and AI are making it possible to predict disease risk earlier and intervene before conditions like heart disease, cancer, and Alzheimer’s develop. Dr. Topol also discusses the science behind “super agers,” people who remain physically and cognitively healthy well into older age, and what research is revealing about the roles of the immune system, inflammation, lifestyle, and emerging therapies in determining how we age. Looking ahead, Dr. Topol shares his perspective on the future of preventive medicine, including how AI-driven prediction, organ-specific aging clocks, and new biological insights could transform healthcare from a reactive system into one focused on keeping people healthy for as long as possible. Thank you for listening! Call to action: If you enjoy The Future of Medicine, subscribe for more conversations with leading scientists shaping the next era of healthcare. Please rate and review the podcast to help others discover these important discussions. Share with friends and colleagues who are curious about how science becomes medicine.

20 years ago, pharmacogenomics was all the buzz: matching specific drugs to our personal DNA was supposed to transform medicine and human health. But here we are 20 years later, and much of that excitement has fizzled. Very few doctors are actually tailoring their treatments to individual patient DNA in the clinic. In this special episode, I talk with Dr. Eric Topol, author of the new book Super Agers, about the promise of pharmacogenomics and the new frontiers of medicine. We talk about how he has always put science first - he shares the story of Vioxx, a pain reliever that he was early to see carried massive risks. Eric put his career on the line to let the world know about the problems. Get full access to Drug Story at www.drugstory.co/subscribe

What if the secret to living well into your 80s and 90s is nothing to do with your DNA? What if the longevity hackers have got it wrong, and it’s actually far more simple than you think to become a ‘super ager’? We all want to live a long, happy and healthy life. But with the vast majority of US and UK people over 60 having at least one chronic disease, the odds are currently stacked against us. Or are they? In this enlightening episode, you’ll learn why healthspan matters more than lifespan – and why it’s never too late, or too early, to take action. My guest is Dr Eric Topol, a practising cardiologist, Professor of Molecular Medicine, and one of the top 10 most cited researchers in medicine. Eric has spent his career at the forefront of genomics and artificial intelligence. Yet in his new book Super Agers: An Evidence-Based Approach To Longevity, he sets out a surprisingly low-tech solution to ageing well. And it’s one that has nothing to do with your parents’ health. In this episode, Eric talks me through what his Wellderly Project – research on remarkably healthy people in their late 80s – revealed about the health metrics that matter. He explains his ‘lifestyle plus’ approach to health, which includes not just the basics like nutrition, exercise and sleep, but evidence-based influences such as environmental toxins, emotional outlook and social connections. His message is an empowering one: making the right choices today could add seven to 10 healthy years to your life, regardless of your family history. We tackle some thought-provoking topics, such as the idea that cancer screening isn’t working, and that forever chemicals and microplastics are far more dangerous than we’ve been led to believe. We discuss the personalisation of healthcare – how knowledge of your own data is the most effective way to drive behaviour change. And Eric shares his positive insights on how AI will be able to help us predict – and take control of – our future health. The ‘big three’ chronic diseases, cancer, heart disease and neurodegeneration, start developing 20 years before we see symptoms. So that’s a big window of time in which you can make a difference to your risk – and a truly empowering message you can start acting on today. Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.   Thanks to our sponsors: https://boncharge.com/livemore https://onepeloton.co.uk   Show notes https://drchatterjee.com/626   DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Dr Eric Topol is a relentless pioneer, a visionary cardiologist, and a groundbreaking scientist who is not merely observing the future of health but actively building it. With a keen focus on leveraging cutting-edge technology and evidence-based science, he challenges the status quo in medicine, pushing for a radical shift from treatment to prevention. His work is reshaping our understanding of longevity, healthspan, and the profound impact of AI, offering a blueprint for a healthier, more informed tomorrow. Takeaways: The "Because" of Prevention: Dr. Topol’s deep-seated motivation stems from witnessing preventable suffering and death within his own family, fueling his drive to transform medicine from a reactive treatment model to a proactive prevention paradigm. Demystifying Superagers: Contrary to common belief, the extraordinary health and longevity of "superagers" are primarily attributed to lifestyle choices and robust immune systems, not solely genetics, offering an empowering message that healthy aging is largely within our control. AI’s Triple Threat in Healthcare: Artificial intelligence is poised to revolutionize healthcare by enhancing diagnostic accuracy, returning valuable time to clinicians by streamlining administrative tasks, and most profoundly, by enabling personalized disease prevention strategies. Sound Bytes: "I just think we can do so much better to prevent the major diseases, not just there that I've been in for my career, cardiovascular, but also neurodegenerative, preventing Alzheimer's and also preventing cancer." "We now are empowered to go that route. And it's a lot like what I experienced in the early 80s, which is when a field within medicine went through a radical change. We need to do that more frequently than every decade or two." "I figured, well, I'm condemned to the same fate. So I've always been interested in genetics and health span, lifespan. And we did a study we called the Welderly. And the Welderly, basically another name for them, are superagers." Connect & Discover Dr Eric: Instagram: @erictopol1 X: @EricTopol Substack: @Ground Truths Book: Super Agers: An Evidence-Based Approach to Longevity LinkedIn: @eric-topol YouTube: @EricTopolSRTI 🔥 Ready to Unleash Your Inner Game-Changer? 🔥  Mick Hunt’s BEST SELLING book, How to Be a Good Leader When You’ve Never Had One: The Blueprint for Modern Leadership, is here to light a fire under your ambition and arm you with the real-talk strategies that only Mick delivers.  👉 Grab your copy now and level up your life → Amazon, Barnes & Noble, Books A Million    FOLLOW MICK ON: Spotify: MickUnplugged Instagram: @mickunplugged  Facebook: @mickunplugged YouTube: @MickUnpluggedPodcast  LinkedIn: @mickhunt  Website: MickHuntOfficial.com Website: howtobeagoodleader.com Website: Leadloudseries.com Apple: MickUnplugged See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What do collagen powders, weighted vests, parasite cleanses, and protein bars all have in common? (According to our favorite no-nonsense doctor, probably a lot less science than TikTok would like you to believe.) This week on Laugh Lines, we’re welcoming back the wonderfully persnickety Dr. Eric Topol to help us debunk the health trends that keep popping up in our feeds (and in our shopping carts.) After our last conversation, we were flooded with listener emails, voicemails, and questions, so this time he is answering all YOUR questions! We cover big topics like brain health, Alzheimer’s prevention, and new blood tests like the “brain clock.” (We also cover cortisol panic, brain booster supplements, and over the top health challenges.) If you are overwhelmed by health advice, tired of feeling like you are doing everything wrong, or just want to laugh while learning what actually matters, this episode will leave you feeling smarter, calmer, and far less tempted to buy supplements while doomscrolling. We love to hear from you! Leave us a message at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube. You can learn more about Dr. Eric Topol here: https://drerictopol.com/ Visit Our Shop Join Our Newsletter Find us on Substack Follow us on Instagram Follow us on TikTok Follow us on Facebook Laugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over three billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Books, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and All You Can Be With ADHD. They were also winners on The Amazing Race (Season 33) on CBS.  Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is hosted by Acast. Thanks for listening! Hosted on Acast. See acast.com/privacy for more information.

Cardiologist and genetic researcher Dr. Eric Topol wrote the book on “Super Agers,” distilling everything that modern medicine can teach us about boosting our immune systems and squeezing more life out of our years – not the other way around. We’ll hear Dr. Topol’s tips for boosting our immune systems and keeping our brains — and guts — running like the biological super-computers they are. And we want to hear from you: What steps are you taking to age well? Guests: Dr. Eric Topol, cardiologist, founder and director of the Scripps Research Institute. His book is "Super Agers: An Evidence-Based Approach to Longevity" Learn more about your ad choices. Visit megaphone.fm/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “A Grand, Unified Theory of Why Americans Are So Unhealthy” originally aired June 18, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com . Host: Derek Thompson Guests: David Kessler and Eric Topol Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Slowing the process of aging is something many people are interested in—and there’s a lot of pseudoscience out there about how to do it. Eric Topol is a cardiologist at Scripps and a prolific researcher on the genetics of longevity. In this episode, Eric debunks some common myths about how to live a longer life and shares his surprising findings about what actually determines a person’s lifespan and healthspan. Adam inquires about the efficacy of health supplements, and he and Eric discuss steps for preventing diseases, the role of AI in medicine, and effective practices for living a longer, healthier life. Host & Guest Adam Grant (Instagram: @adamgrant | LinkedIn: @adammgrant | Website: https://adamgrant.net/) Eric Topol (Instagram: @erictopol1 | Website: https://drerictopol.com/)  Links Books: https://drerictopol.com/books/ Substack: https://erictopol.substack.com/ Follow TED!  X: https://www.twitter.com/TEDTalks Instagram: https://www.instagram.com/ted Facebook: https://facebook.com/TED LinkedIn: https://www.linkedin.com/company/ted-conferences TikTok: https://www.tiktok.com/@tedtoks  Podcasts: https://www.ted.com/podcasts For the full text transcript, visit https://www.ted.com/podcasts/worklife-transcripts Hosted on Acast. See acast.com/privacy for more information.

Slowing the process of aging is something many people are interested in—and there’s a lot of pseudoscience out there about how to do it. Eric Topol is a cardiologist at Scripps and a prolific researcher on the genetics of longevity. In this episode, Eric debunks some common myths about how to live a longer life and shares his surprising findings about what actually determines a person’s lifespan and healthspan. Adam inquires about the efficacy of health supplements, and he and Eric discuss steps for preventing diseases, the role of AI in medicine, and effective practices for living a longer, healthier life. Host & Guest Adam Grant (Instagram: @adamgrant | LinkedIn: @adammgrant | Website: https://adamgrant.net/) Eric Topol (Instagram: @erictopol1 | Website: https://drerictopol.com/)  Links Books: https://drerictopol.com/books/ Substack: https://erictopol.substack.com/ Follow TED!  X: https://www.twitter.com/TEDTalks Instagram: https://www.instagram.com/ted Facebook: https://facebook.com/TED LinkedIn: https://www.linkedin.com/company/ted-conferences TikTok: https://www.tiktok.com/@tedtoks  Podcasts: https://www.ted.com/podcasts ReThinking is produced by Cosmic Standard. Our Senior Producer is Jessica Glazer, our Engineer is Aja Simpson, our Technical Director is Jacob Winik, and our Executive Producer is Eliza Smith. For the full text transcript, visit ted.com/podcasts/rethinking-with-adam-grant-transcripts Hosted on Acast. See acast.com/privacy for more information.

What’s the secret to living longer and better? (Spoiler: It’s not a cold plunge or protein popcorn.) In this episode, we sit down with the brilliant Dr. Eric Topol — cardiologist, scientist, and author of Super Agers — to separate fact from fiction in the world of longevity. We learn that blood tests are getting really good, GLP-1 drugs show real promise, and to always call Dr. Topol before you buy something TikTok tells you to. We cover everything from protein myths, weighted vests, and saunas to tests that could one day prevent Alzheimer’s and cancer. Penn and I also cover sleep tips, landlines, and Max Headroom. (Gen Xers, you get it.) We hope this episode leaves you smarter, calmer, and surprisingly optimistic about the future of aging. We love to hear from you, leave us a message at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube. Visit Our Shop Join Our Newsletter Find us on Substack Follow us on Instagram Follow us on TikTok Follow us on Facebook Laugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over two billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Books, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and All You Can Be With ADHD. They were also winners on The Amazing Race (Season 33) on CBS.  Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is hosted by Acast. Thanks for listening! Hosted on Acast. See acast.com/privacy for more information.

Interview: Dr Eric Topol (Part 2) In the second half of our conversation, Dr Eric Topol discusses AI’s promise in reducing clinician burnout, forecasting disease, and reshaping prevention. He also reflects on 13 years since The Creative Destruction of Medicine , shares his favourite transformative tools, and offers advice for clinicians seeking creative careers Australian CDC – the data angle Australia is finally moving ahead with its own Centre for Disease Control, promising better national coordination and public health data sharing. But will it deliver transparency and timely insights—or just more bureaucracy? AI & Fertility – SpermSearchAI delivers first UAE pregnancy An AI tool developed in Australia, by NeoGenix Biosciences, has achieved its first pregnancy in the UAE. The technology speeds up and improves IVF outcomes, showing how Australian health innovation is going global. US Information Blocking Enforcement The US Department of Health and Human Services will finally enforce penalties for health providers and IT vendors who block patient access to their own records. A big step for patient rights, and a reminder of how far Australia still has to go. Apple’s Health Tech Push Apple’s new Watch Series 11 now measures blood pressure and the latest AirPods can track heart rate. These updates blur the line between wellness gadgets and medical devices, raising big questions about accuracy, equity, and data overload. Eli Lilly’s AI Drug Discovery Giveaway Pharma giant Eli Lilly is making its drug discovery language models publicly available through “Lilly TuneLab.” It’s part open-science, part strategic play—accelerating research while still funnelling insights back to Lilly. Australian Robotics – Abi the Care Robot Melbourne startup Andromeda has raised $23m to scale Abi, a friendly robot designed for aged care and children’s hospitals. Founder Grace Brown, just 25, has quickly become one of Australia’s standout young innovators. Resources: Dr Eric Topol’s book SuperAgers Link Dr Eric Topol’s podcast & substack Ground Truths Link Medicine and the Machine podcast with Dr Abraham Verghese and Dr Eric Topol Link Book recommendation: The AI Valley, Gary Rivlin Link Recommended FREE course: AI in Healthcare from RCSI Link Recommended FREE course: Patient Insights Masterclass by Savvy Corporate Link Visit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news. Follow us on LinkedIn Louise | George | Pulse+IT Follow us on BlueSky Louise | George | Pulse+IT Send us your questions pulsepod@p

This episode is brought to you by One Skin and Momentous . Cardiovascular disease remains the leading cause of death worldwide. But today, we no longer have to wait for symptoms to understand our risk. Advances in technology now make it possible to get a clear snapshot of individual risk, not only for heart disease, but also for cancer and neurodegenerative conditions, empowering us to take proactive steps to lower risk and support long-term health. Our guest today breaks down what’s truly worth investing in and what we can skip. Today on The Dhru Purohit Show , Dhru sits down with Dr. Eric Topol, a cardiologist and Professor of Molecular Medicine at the Scripps Research Institute. Dr. Topol shares insights on the importance of preventive health, with a focus on cardiovascular disease, cancer, and neurodegenerative conditions. He explains the role of polygenic risk scores in assessing individual risk, explores the strengths and limitations of various testing methods, and highlights how lifestyle choices shape disease prevention. Dhru and Dr. Topol also discuss emerging technologies in health monitoring, the influence of environmental factors like air pollution, and what the future may hold for aging and health management. Dr. Eric Topol is Executive Vice President and Professor of Molecular Medicine at Scripps Research and founder of the Scripps Research Translational Institute. A practicing cardiologist and one of the ten most-cited researchers in medicine, he is renowned for his wor in AI, genomics, and digital clinical trials. Named to the Time 100 Health list in 2024, he also writes the Ground Truths newsletter and is the author of The Creative Destruction of Medicine , The Patient Will See You Now , Deep Medicine , and Super Agers . In this episode, Dhru and Dr. Topol dive into: Cardiovascular disease causes, risks, and prevention (1:07) Polygenic risk genetic links to disease and understanding your risk (7:56) Heart health with Dr. Topol’s key recommendations (13:21) Cancer testing types of tests and how to approach results (27:47) Medical guidance mistrust, confusion, incidental findings, and the importance of evidence-based practitioners (34:20) Alzheimer’s detection, blood work, testing, and the role of AI (43:13) Environmental risks, air pollution, and sleep irregularity, and why these factors must be addressed (53:20) Parkinson’s disease: the fastest-growing neurodegenerative condition (57:01) Prevention and lowering your risk of developing major diseases (59:52) Gut health and the gut-hormone connection (1:02:05) Aging and immunity: links between age-related diseases and the immune system (1:06:19) Measuring biological age (1:08:14) Final thoughts and takeaways (1:16:27) Also mentioned in this episode: Super Agers: An Evidence-Based Approach to Longevity Polygenic Risk Scores: Ready for Prime Time? What a Polygenic Risk Score Can and Can’t Tell You Allelica Polygenic Risk Test Dhru’s APOE Chat GPT Results <

What if the products you use every day, the air you breathe, and the food you eat is making you sick?  Today, Mel speaks with Dr. Eric Topol, MD, one of the most cited scientists and researchers in the world, about the hidden toxins in your environment that are silently hijacking the health of you and your family. Dr. Topol shares the alarming truth about the microplastics and forever chemicals that are all around you, and how they’re linked to skyrocketing rates of infertility, cancer in young people, heart disease, and even cognitive decline.  Most importantly, he will share the exact products and chemicals to watch out for, how to avoid them, and the simple changes you can make right now to protect you and your kids.  You will learn: -Why microplastics are showing up in your arteries, brain, and reproductive system, and what that means for you  -The connection between forever chemicals and diseases like diabetes, dementia, and cancer  -Which everyday products in your kitchen, bathroom, and home may be silently making you sick  -How to read labels so you know what’s safe, and what’s not  -And the 3 most important changes you can make right now to reduce your exposure and protect your family  This episode is both a wake-up call and a guide.  You’ll walk away not only understanding the invisible threats in your environment, but also with simple, practical steps you can take to safeguard your health and longevity.  For more resources, click here for the podcast episode page.  If you liked the episode, check out Dr. Eric Topol’s first appearance on The Mel Robbins Podcast: Advice From the #1 Longevity Doctor: Add 10 Years to Your Life With 3 Simple Habits Connect with Mel:    Get Mel’s #1 bestselling book, The Let Them TheoryWatch the episodes on YouTubeFollow Mel on InstagramThe Mel Robbins Podcast InstagramMel's TikTokSign up for Mel’s personal newsletterSubscribe to SiriusXM Podcasts+ to listen to new episodes ad-freeDisclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Howie and Harlan are joined by physician, scientist, and author Eric Topol to discuss his new book, Super Agers: An Evidence-Based Approach to Longevity ; the potential of individualized polygenic risk scores; and the dangers of the protein craze. Links: Health & Veritas Ep. 58: Dr. Eric Topol: Pushing Medicine into the Future Eric Topol: Super Agers: An Evidence-Based Approach to Longevity Eric Topol: "The Drivers of Age-Related Diseases" Eric Topol: "A Review of Outlive " Eric Topol, Ground Truths podcast: "Peter Attia: Our conversation about his hit book Outlive , Medicine 3.0, promoting healthspan, GLP-1 drugs and more" Eric Topol: The Creative Destruction of Medicine Eric Topol: The Patient Will See You Now Eric Topol: Deep Medicine Eric Topol: "Our Preoccupation With Protein Intake" The Daily podcast: "How America Got Obsessed with Protein" "High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy" "Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk" "5 Takeaways From Kennedy's Senate Hearing" Eric Topol on the Dr. Hyman Show: "How AI Could Change Your Next Doctor Visit Forever!" Eric Topol: "The Business of Promoting Longevity and Healthspan" The Age of the Infovore: Succeeding in the Information Economy Eric Topol, Ground Truths podcast: "Tyler Cowen: The Prototypic Polymath" "How a scientist who studies 'super agers' exercises for a longer life" Eric Topol: "Our Sleep, Brain Aging, and Waste Clearance" "Alzheimer's genes: Are you at risk?" Eric Topol: "The Breakthrough Blood Test for Alzheimer's Disease" Eric Topol: "Predicting and preventing Alzheimer's disease" Eric Topol: "The personal and clinical

Interview: Dr Eric Topol (Part 1) We’re joined by Dr Eric Topol—cardiologist, scientist, author, and global digital health leader. In part one, Eric shares his journey from clinician to digital health pioneer, his vision for “SuperAgers,” and why genomics and personalised medicine could redefine how long—and how well—we live Chatbots for Patients We discuss the Wall Street Journal’s bold claim that chatbots could become part of the medical team. From spotting errors to translating lab results and reminding patients about medications, can they really serve as low-risk, always-on companion? Questions remain around accuracy, empathy, and whether they truly add value or just more noise. The Human Side of Interoperability Inspired by Amy Gleason’s LA Times op-ed, we look at the personal impact of fragmented health systems. Her daughter’s care journey shows how disconnected records hinder outcomes—and how AI uncovered a hidden opportunity. Should we lean into more personal stories to communicate to a wider audience? Meta & Who Owns Your Health Data? A San Francisco jury found Meta guilty of illegally harvesting data from millions of Flo app users—menstrual cycles, ovulation, even pregnancy intentions. The ruling highlights urgent questions: Who really owns health data, and what rights do patients have when tech giants treat it like ad fuel? Patient Consent in the Age of AI Consent forms are broken—static, outdated, and unfit for the AI era. We unpack Y. Tony Yang’s American Journal of Bioethics piece arguing for “dynamic consent,” accountability frameworks, and real patient understanding. Without rethinking consent, healthcare risks losing trust as AI tools grow more influential Black Box for Aged Care What if aged care had a “black box,” like aviation? Sensors, AI, and monitoring systems could flag risks before crises hit. A Pulse+IT blog argues for shifting from reactive to proactive care, but business models and adoption lag behind. We debate whether the sector can finally move from inquiry to prevention Resources: Louise’s LinkedIn poll on gen AI use for health research Link Dr Eric Topol’s book SuperAgers Link Y. Tony Yang’s American Journal of Bioethics Article on Patient Consent Link Aged Care’s Black Box in Pulse+IT Link Amy Gleason’s parental perspective on the need for health data interoperability Link Visit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news.

In this conversation, Michael Shermer and Dr. Eric Topol discuss the realties of aging, with particular focus on the role of AI in enhancing patient care and disease prevention, the importance of lifestyle factors, and the limitations of genetic testing in predicting health outcomes. Topol also explains the dangers of ultra-processed foods, their link to inflammation, and the role of GLP-1 drugs in promoting healthier eating habits. The conversation also covers diet, particularly the differences between chicken and red meat, and the significance of sleep for overall health. Plus, consumption of microplastics, cholesterol management and statins, the critical role of social connections in maintaining mental and physical health, and the future of personalized medicine in cancer prevention. Eric Topol is a cardiologist and one of the top ten most cited researchers in medicine, known for his groundbreaking studies on AI in medicine, genomics, and digitized clinical trials. Topol is also the executive vice president and a professor of molecular medicine at Scripps Research, the largest nonprofit biomedical institute in the United States. He was named one of the Top 100 most influential people in health in 2024 by Time. His new book is Super Agers.

Medicine stands at the threshold of a new era, where artificial intelligence and systems biology are working hand in hand to make care more personal, predictive, and precise than ever before. AI is already improving diagnostic accuracy, automating administrative tasks, and uncovering patterns in data—like retinal scans or genomics—that humans often miss. Rather than replacing doctors, AI enhances their ability to deliver more informed, precise, and efficient care. At the same time, individuals are gaining tools—from at-home diagnostics to wearable biosensors—that empower them to track and optimize their own health. This shift marks a move from reactive, disease-centered care to a proactive, data-driven model of scientific wellness. In this episode, I talk with Dr. Eric Topol, Dr. Nathan Price, Dr. Leroy Hood, Dr. Vijay Pande, and Daisy Wolf about how artificial intelligence, personalized data, and wearable technology are converging to radically transform medicine. Dr. Eric Topol is Executive Vice President of Scripps Research and founder/director of its Translational Institute, recognized as one of the top 10 most cited researchers in medicine with over 1,300 publications. A cardiologist and author of several bestselling books on the future of medicine, he leads major NIH grants in precision medicine and shares cutting-edge biomedical insights through his Ground Truths newsletter and podcast. Dr. Nathan Price is Chief Scientific Officer at Thorne HealthTech, author of The Age of Scientific Wellness, and a National Academy of Medicine Emerging Leader. He also serves on the Board on Life Sciences for the National Academies and is Affiliate Faculty in Bioengineering and Computer Science at the University of Washington. Dr. Leroy Hood is CEO and founder of Phenome Health, leading the Human Phenome Initiative to sequence and track the health of one million people over 10 years. A pioneer in systems biology and co-founder of 17 biotech companies, he is a recipient of the Lasker Prize, Kyoto Prize, and National Medal of Science. Dr. Vijay Pande is a General Partner at Andreessen Horowitz and founder of a16z Bio + Health, managing over $3 billion in life sciences and healthcare investments at the intersection of biology and AI. An Adjunct Professor at Stanford, he is known for his work in computational science, earning honors like the DeLano Prize and a Guinness World Record for Folding@Home. Daisy Wolf is an investing partner at Andreessen Horowitz, specializing in healthcare AI, consumer health, and healthcare-fintech innovation. She previously worked at Meta and in various startups, holds a JD from Yale Law, an MBA from Stanford, and a BA from Yale, and is based in New York City. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Can AI Fix Our Health and Our Healthcare System? The Next Revolution In Medicine: Scientific Wellness, AI And Disease Reversal The Future of Healthcare: The Role of AI and Technology

On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer’s and other chronic diseases before they start. This is one of the most hopeful conversations I’ve had about what’s ahead. Watch it on YouTube here. We discuss: • How new diagnostics and AI tools could help detect Alzheimer’s early • The key lab tests and biomarkers to know—and how to talk to your doctor about them • Why tracking your health data over time matters more than you think • What you can do to strengthen your immune system and lower disease risk We have more power than ever to take control of our health. This episode shows you where to start. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Pique, fatty15 and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Receive 20% off FOR LIFE + a free Starter Kit with a rechargeable frother and glass beaker at Piquelife com/Hyman. Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit.Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Gil and Eric discuss Eric’s book, Super Agers, and the inspiration behind it: a 98-year-old patient who exemplified healthy aging. They explore the five dimensions of healthspan optimization: lifestyle, omics, the immune system, and the role of data and AI in personalized medicine. Eric highlights how AI can analyze multi-layered data to provide personalized recommendations for preventing age-related diseases. The conversation also explores the importance of exercise, sleep, and social connection for healthy aging, as well as the risks associated with high-dose statins. Eric emphasizes the need for a shift towards preventative care, using data and AI to identify and address individual risks. He stresses the power of lifestyle changes, rather than supplements, in improving long-term health outcomes. Guest-at-a-Glance 💡 Name: Dr. Eric Topol 💡 What they do: Founder and Director 💡 Company: Scripps Research Translational Institute 💡 Noteworthy: Genomics pioneer, digital medicine innovator, and preventative care advocate Episode highlights: [00:00] The Impact of Social Isolation on Health [01:19] Meet Dr. Eric Topol: A Pioneer in Medicine [03:16] Dr. Topol's Personal Journey into Medicine [05:31] The Early Days of Genetic Therapy [07:54] Insights from Dr. Topol's Book: Super Agile [13:02] The Role of Genetics in Longevity [14:22] The Five Dimensions of Healthspan [20:08] The Power of Exercise and Diet [23:58] The Truth About Supplements [32:38] The Importance of Sleep [36:07] The Value of Social Relationships [38:02] The Benefits of Nature and Social Interaction [39:17] Exploring Longevity Drugs: Metformin and Rapamycin [40:10] Risks and Benefits of Longevity Treatments [41:56] The Potential of GLP-1 Drugs [46:41] Statins and Their Impact on Health [51:11] Emerging Cancer Detection Technologies [56:15] The Role of AI and Polygenic Scores in Healthcare [57:36] Preventing Alzheimer's Disease [01:01:14] The Future of Longevity and Healthspan We Appreciate You! As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: https://info.insidetracker.com/podcast For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

The world today is oversaturated with trends, tips, and treatments for how to live long and be healthy while doing it. But it can be hard to know who to listen to – and what actually works. In this episode, we talk to Dr. Eric Topol, renowned cardiologist and author of the book Super Agers: An Evidenced-Based Approach to Longevity, to clear up some of the myths around healthy aging and shine light on what actually works. We cover everything from how much sleep you need and how much movement to get, to dietary advice and the benefits of social engagement — and much more. 

What if we stopped trying to cure disease and started preventing it instead? In this episode, Eric Topol, founder and director of the Scripps Research Translational Institute and a cardiologist, scientist, and author, joins a16z general partner Vijay Pande to unpack the future of aging, prevention, and precision health—as explored in Eric's new book, Super Agers: An Evidence-Based Approach to Longevity. Together, they discuss AI-driven risk prediction and next-gen immunotherapies — a roadmap for how we could eliminate age-related diseases before they begin. From the transformative potential of GLP-1 drugs to organ-specific aging clocks, this episode is about the innovations with the potential to expand healthspan, not just lifespan. Learn more about a16z Bio+HealthLearn more about & Subscribe to Raising HealthFind a16z Bio+Health on LinkedInFind a16z Bio+Health on X Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Eric Topol (Super Agers: An Evidence-Based Approach to Longevity) is a cardiologist, researcher, and author. Eric returns to the Armchair Expert to discuss being Monica’s epilepsy consultant after their early interview, recent findings suggesting that AI aids doctors in providing better care, and an intense gag order suppressing getting a detrimental drug taken off the market. Eric and Dax talk about hospital beds that can monitor people as they sleep, no one having yet done a healthy aging study of genomics, and the true anecdote that inspired him to write his new book. Eric explains creating a segue to effectively prevent diseases we never could before, how Viagra was initially a failed blood pressure medication, and why despite troubling trends in diseases he remains optimistic about the future of aging. Follow Armchair Expert on the Wondery App or wherever you get your podcasts. Watch new content on YouTube or listen to Armchair Expert early and ad-free by joining Wondery+ in the Wondery App, Apple Podcasts, or Spotify. Start your free trial by visiting wondery.com/links/armchair-expert-with-dax-shepard/ now. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I'll teach you how to become the media's go-to expert in your field. Enroll in The Professional's Media Academy now: https://www.professionalsmediaacademy.com/ Huge thanks to Dr. Eric Topol for coming on the show. Pick up a copy of his new book "Super Agers" here: https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666 Follow Dr. Topol on Twitter/X: https://x.com/erictopol 00:00 Intro 01:12 The Absence Of Doctors Online 08:26 Full Body MRI / Peter Attia 18:21 Bryan Johnson / Deep Sleep 23:38 Hyper-Optimization / Biological Clock 28:37 Alzheimer's / Ozempic 40:05 Changing Guidelines 41:52 Continuous Glucose Monitors 48:22 Predatory Health Creators Online 53:37 RFK Jr. 1:02:14 Anti-vaxxers 1:07:48 NIH Cuts 1:18:42 Over-Processed Foods 1:24:27 AI 1:37:46 Tips For Longevity 1:46:38 Wearables / Trackers Help us continue the fight against medical misinformation and change the world through charity by becoming a Doctor Mike Resident on Patreon where every month I donate 100% of the proceeds to the charity, organization, or cause of your choice! Residents get access to bonus content, an exclusive discord community, and many other perks for just $10 a month. Become a Resident today:https://www.patreon.com/doctormike Let’s connect:IG: https://go.doctormikemedia.com/instagram/DMinstagram Twitter: https://go.doctormikemedia.com/twitter/DMTwitter FB: https://go.doctormikemedia.com/facebook/DMFacebook TikTok: https://go.doctormikemedia.com/tiktok/DMTikTok Reddit: https://go.doctormikemedia.com/reddit/DMReddit Contact Email: DoctorMikeMedia@Gmail.com Executive Producer: Doctor Mike Production Director and Editor: Dan Owens Managing Editor and Producer: Sam Bowers Editor and Designer: Caroline Weigum Editor: Juan Carlos Zuniga * Select photos/videos provided by Getty Images *** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional **

While promises of extending the human lifespan to 125 and beyond are premature, recent breakthroughs in the early detection of killer diseases of the major organs and brain offer a healthier old age – especially when paired with behavioral changes that Dr Topol calls “Lifestyle+.”

Medical science is advancing at an astonishing rate. Today we talk with leading expert Eric Topol about two aspects of this story. First, the use of artificial intelligence in medicine, especially in diagnostics. This is an area that is a perfect match between an important question and the capabilities of machine learning, to the point where AI can out-perform human doctors. And second, our understanding of aging and what to do about it. Eric even gives some actionable advice on how to live more healthily into our golden years. Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/05/05/episode-313-eric-topol-on-the-changing-face-of-medicine-and-aging/ Support Mindscape on Patreon. Eric Topol received and M.D. from the University of Rochester. He is currently the Gary and Mary West Chair of Innovative Medicine in the Department of Translational Medicine at Scripps Research. He is also the Founder, Scripps Research Translational Institute, and Senior Consultant, Scripps Clinic, Division of Cardiovascular Diseases. Among his awards are the Hutchinson Medal from the University of Rochester and membership in the National Academy of Sciences. His books include Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again, and Super Agers: An Evidence-Based Approach to Longevity. Web site Scripps web page Google Scholar publications Wikipedia Substack Bluesky

In the first episode of Fixing Healthcare ’s 10th season, cohosts Dr. Robert Pearl and Jeremy Corr speak with Dr. Eric Topol , a healthcare visionary and global technology leader. This season focuses on the future of technology in healthcare, a topic close to Dr. Pearl’s heart. His newest book, ChatGPT, MD: How AI-Empowered Patients & Doctors Can Take Back Control of American Medicine , debuted as an Amazon top new release. All profits from the book go to Doctors Without Borders. Dr. Topol is a renowned cardiologist and founder of the Scripps Research Translational Institute. He has been a pioneer in predicting how technology will shape the future of medicine. His bestselling book, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again , explores the transformative power of AI in healthcare. During the interview, Dr. Topol highlights three ways technology will break the traditional rules of medicine: Precision Preventive Care : Dr. Topol emphasizes that AI will revolutionize preventive care by moving beyond the outdated practice of relying solely on age and sex to determine who needs screening. Instead, generative AI will analyze vast datasets, including polygenic risk scores, biomarkers and proteomic data, to identify individuals at the highest risk of developing life-threatening diseases like cancer or heart disease. This proactive approach will allow for targeted prevention, significantly improving outcomes. Reducing Misdiagnoses : The conversation turns to the persistent issue of diagnostic errors, a leading cause of preventable harm in healthcare. Dr. Topol discusses how AI can alleviate this problem by giving clinicians more time to think critically, providing deep analysis of patient data and interpreting medical images with unparalleled accuracy. This would dramatically reduce the current rate of misdiagnoses, which remains a significant life ending failure in healthcare. Transforming Clinical Documentation : Dr. Topol also explores how generative AI is already freeing from the burden of administrative tasks, particularly documentation. By automating the creation of high-quality electronic health records from conversations between doctors and patients, AI will allow clinicians to focus more on patient care, improving both efficiency and the patient experience. Throughout the episode, Drs. Topol and Pearl discuss the broader implications of these technologies, including the potential to revolutionize medical research, the challenges of data security and the cultural shift required in healthcare to fully embrace these innovations. Tune in for the full interview and join the conversation on social media. * * * Fixing Healthcare is a co-production of Dr. Robert Pearl and Jeremy Corr . Subscribe to the show via Apple, Spotify, Stitcher or wherever you find podcasts. Join the conversation or suggest a guest by following the show on Twitter and LinkedIn . The post FHC #146: Dr. Eric Topol on how AI is changing healthcare appeared first on Fixing Healthcare .

View the Show Notes For This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Get Ad-free Episodes & Dr. Hyman+ Audio Exclusives Dr. Eric Topol is the Founder and Director of the Scripps Research Translational Institute, Professor of Molecular Medicine, and Executive Vice-President of Scripps Research. He has published over 1,200 peer-reviewed articles with more than 330,000 citations, was elected to the National Academy of Medicine, and is one of the top 10 most cited researchers in medicine. His principal scientific focus has been on individualized medicine using genomic, digital, and AI tools. This episode is brought to you by Rupa Health, Pendulum, Thrive Market, and Fatty15. Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com. Pendulum is offering listeners 20% off their first month’s subscription of Akkermansia for gut health. Visit PendulumLife.com and use code HYMAN. Head over to thrivemarket.com/Hyman today to receive 30% off your first order and a free gift up to $60. Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 10% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started. In this episode we discuss (audio version / Apple Subscriber version): The first phase of AI’s application in medicine (7:19 / 5:40) How medicine will incorporate AI over the next few years (9:59 / 8:19) Retinal imaging (16:45 / 15:05) Expert-informed AI (20:02 / 18:23) The impending and biggest shake-up in the history of medicine (22:18 / 20:38) How AI can improve issues of medical error (26:08 / 24:29) Using AI to personalize medicine and prevent disease (33:01 / 29:11) The obesity crisis and toxic food environment (41:04 / 37:14) How AI can help restore the patient-doctor relationship (46:53 / 43:03) Using AI as a guide for medical self care (50:34 / 46:44) Reimagining research in the era of AI-enabled medicine (56:58 / 53:07) Dr. Topol’s Substack, Ground Truths. Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again