Shannon HallEvery podcast appearance, updated as new ones drop

Powered by Protein Production Technology International Moving from pilot-scale success to profitable industrial production remains one of the biggest challenges in industrial biotechnology. A process that works in the lab may encounter very different realities at commercial scale, from oxygen transfer and energy use to downstream processing, production costs, and reliable supply. In this episode of the Protein Production Technology International Podcast, Nick Bradley is joined by experts from Bühler, Pular Group, Vivace, Pow.Bio, ADM, and Fermentalg to explore what it takes to turn promising biotechnologies into commercially viable businesses. The discussion examines why proving that a product can be made is only the beginning. The real challenge is producing it reliably, competitively, and at a cost customers are willing to pay. The panel explores the gap between technical feasibility and commercial success, including the importance of manufacturing strategy, infrastructure, production economics, and knowing where continued investment can make a difference. Bühler shares its perspective on connecting biology with a complete production system, helping companies address the engineering and operational challenges that emerge during scale-up. The conversation also highlights the importance of designing processes with commercial production in mind, rather than treating industrialization as a problem to solve only after success in the lab or pilot plant. The panel considers the role of customer demand, reliable supply chains, and partnerships in building a viable industrial biotechnology sector. From bio-based ingredients and precision fermentation to proteins, oils, and fats, speakers discuss the opportunities emerging as biological production moves toward larger-scale applications. The conversation also explores why the industry’s next phase will depend on more than scientific breakthroughs. Commercial discipline, scalable technology, and the ability to deliver value for customers will be essential to turning industrial biotechnology’s potential into profitable production. The Future of Protein Production is connecting companies working to make the global protein system more sustainable, kind and fair for the planet, people, and animals. To find out more about our platform click here: https://www.futureofproteinproduction.com/ To read the most recent edition of Protein Production Technology, our multi-media magazine, click here: https://www.futureofproteinproduction.com/ #FutureOfProteinProduction #ProteinProductionTechnology #Buhler #IndustrialBiotechnology #ScaleUp #PrecisionFermentation #Biomanufacturing #AlternativeProteins #BioBased #FoodTech #Biotechnology #Fermentation #FoodInnovation

In this episode of the PPTI podcast, Shannon Hall, Co-Founder at Pow.bio, and Thierry Duvanel, Director of Innovation at Bühler Group, discussed how a new partnership between a startup and a global engineering company is tackling one of industrial biomanufacturing’s biggest challenges: the slow and capital-intensive path from concept to scale. Hall explained how continuous fermentation, combined with model-driven control, has moved beyond early pilot projects and is now being developed as a platform that can be implemented within existing facilities to improve productivity, uptime, and process reliability. Duvanel explored why conventional batch systems often struggle to scale efficiently, and how integrated continuous approaches could improve asset utilization without requiring major new capital investment. The discussion also addressed common misconceptions around continuous operations, the realities of running infrastructure on a 24/7 basis, and the role of AI-supported decision-making in improving first-run performance under varying site conditions. Together, they outlined how this approach could offer a more predictable, modular, and scalable pathway for fermentation companies moving toward industrial production. Powered by Protein Production Technology International