Jennifer DoudnaEvery podcast appearance, updated as new ones drop

Nobel laureate Jennifer Doudna, co-inventor of CRISPR, is pushing the frontier of gene editing in San Francisco’s Mission Bay, where her revolutionary tech now powers personalized medicine. While AI-driven drug discovery gains traction, Doudna remains skeptical it can independently spark breakthroughs—true innovation still demands human insight. She warns that editing human traits like intelligence is far more complex than imagined, involving countless genes and environmental variables. Despite CRISPR’s current hurdles—cost, imprecision, and patient discomfort—new advances are emerging, including a breakthrough from Columbia University. The first CRISPR-based therapy for sickle cell disease just received FDA approval, signaling a new era in genetic medicine. Support the show: Get a discount at https://solipillow.com/discount/dnn. Advertise on DNN: advertise@thednn.ai This is an automated, high-level news summary based on public reporting. Report issues to feedback@thednn.ai. View sources & latest updates: https://sources.thednn.ai/cb9a07f42f18c518

We live in a moment when the power to change the world often arrives before the wisdom to understand that power. CRISPR, a bacterial immunity process turned DNA editing tool, promises breakthroughs across scientific disciplines. But it also collapses long-standing boundaries between nature and human design. In this episode, Jennifer Doudna – Nobel Prize-winning chemist and founder of the Innovative Genomics Institute – reflects on the thrilling discovery of CRISPR as a gene-editing tool and what it means to suddenly possess the ability to edit the code of life itself. From the ongoing explosion of new opportunities to the shock of seeing ethical boundaries crossed in real time, is there a safe path forward in shaping the future of biological life as we know it? Subscribe to the Berggruen Institute on YouTube to be the first to listen to new Futurology episodes: https://www.youtube.com/@Berggrueninst Catch up on the Futurology conversation with full episodes on YouTube. https://www.youtube.com/playlist?list=PLyYCSKWs8iYgjg-mhu-EuhTrG0-adrb0c Apple Podcasts https://podcasts.apple.com/us/podcast/futurology/id1821718921 Spotify https://open.spotify.com/show/2I38HvHP6KlXrD5ysfygxk?si=XB2qyyGjT2ONMTd5XUKJAg&nd=1&dlsi=ac8cda6751834298 Mentioned in this Episode: The Double Helix — James D. Watson (Book, 1968) https://www.simonandschuster.com/books/The-Double-Helix/James-D-Watson/9780743216302 The Pleasure of Finding Things Out — Richard P. Feynman (Book, 1999) https://www.hachettebookgroup.com/titles/richard-p-feynman/the-pleasure-of-finding-things-out/9780465023951/ “The RNA World” — Walter Gilbert (Article, 1986) https://www.nature.com/articles/319618a0.pdf A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity — Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A. Doudna, Emmanuelle Charpentier (Paper, 2012). https://www.science.org/doi/10.1126/science.1225829 “Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos” — Niu et al. (Paper, 2014) https://www.cell.com/fulltext/S0092-8674(14)00171-6 Infant with rare, incurable disease is first to successfully receive personalized gene therapy treatment – (Article, May 2025) https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatment Human Genome Editing: Science, Ethics, and Governance — National Academies (Report, 2017) https://nap.nationalacademies.org/catalog/24623/human-genome-editing-science-ethics-and-governance “Can CRISPR Cut Methane Emissions From Cow Guts?” — UC Davis (Article, 2023) https://www.ucda

This week, we’re bringing you the first episode of Season 3 of the podcast ON CRISPR. Walter Isaacson — the bestselling biographer behind Musk, Einstein and Steve Jobs – and journalist Evan Ratliff (Shell Game, Mastermind, Longform) take a behind-the-scenes look at the story of Jennifer Doudna, one of the scientific pioneers behind the gene editing software, CRISPR. In this episode, Evan sits down with Walter Isaacson to discuss Doudna’s upbringing, the history of DNA’s discovery and gene editing, and Baby KJ, a CRISPR patient who represents a milestone for both researchers and patients. See omnystudio.com/listener for privacy information.

Join a full house at the Sydney Opera House with Nobel winning scientist Jennifer Doudna and Big Ideas' presenter Natasha Mitchell to discuss the huge social, ethical, and scientific implications of the CRISPR gene editing revolution her groundbreaking discovery with Emmanuelle Charpentier and colleagues kicked off. From curative therapies to gene edited babies - will we use it to hack our own evolution - are we already? This event was presented in 2024 by the Sydney Opera House , Big Questions Institute (BQI), Sydney Writers’ Festival , UNSW Sydney . Original publication: 24 July 2024 Speaker: Professor Jennifer Doudna 2020 Nobel Prize for Chemistry co-winner Li Ka Shing Chancellor’s ChairProfessor, Departments of Chemistry and of Molecular and Cell BiologyFounder, Innovative Genomics Institute University of California, BerkeleyInvestigator, Howard Hughes Medical InstituteSenior investigator, Gladstone Institutes Further information and listens: Doudna Lab Jennifer Doudna in conversation with Natasha Mitchell at an event in 2018 World's first CRISPR gene edited babies born - are we ready?(2018 Science Friction episode with Natasha Mitchell) The CRISPR gene-edited babies and the doctor who made them - what really happened? (2019 Science Friction episode with Natasha Mitchell) Out of jail, is the CRISPR-baby scandal scientist at it again? (2023 Science Friction episode with Natasha Mitchell) Feral science or solution? Unleashing gene drives (Science Friction episode with Natasha Mitchell) Making happier animals? Gene editing in the farmyard (Science Friction episode with Natasha Mitchell) Hear Natasha Mitchell learn how to do CRISPR gene editing in 2016 (as part of a 4-part Earshot series The Hidden History of Eugenics, Part 1 , Part 2 , Part 3 , Part 4 ) The science and ethics of genome editing with Jennifer Doudna and Kevin Esvelt (video of event hosted by Natasha Mitchell in 2018) Natasha Mitchell's review of Siddhartha Mukherjee's The Gene: An Intimate History

The world is on the cusp of extraordinary changes - from cures for intractable illnesses to dramatic reductions in greenhouse gasses - thanks to Nobel Prize winner Jennifer Doudna. Listen to her thoughts in this fascinating discussion with Natasha Mitchell and learn about the benefits and threats in the revolution of gene editing. This event was recorded live at Sydney Opera House on 21 May 2024. Hosted on Acast. See acast.com/privacy for more information.

Join Professor Hannah Fry at the AI for Science Forum for a fascinating conversation with Google DeepMind CEO Demis Hassabis. They explore how AI is revolutionizing scientific discovery, delving into topics like the nuclear pore complex, plastic-eating enzymes, quantum computing, and the surprising power of Turing machines. The episode also features a special 'ask me anything' session with Nobel Laureates Sir Paul Nurse, Jennifer Doudna, and John Jumper, who answer audience questions about the future of AI in science. Watch the episode here, and catch up on all of the sessions from the AI for Science Forum here . Please leave us a review on Spotify or Apple Podcasts if you enjoyed this episode. We always want to hear from our audience whether that's in the form of feedback, new idea or a guest recommendation! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, we listen to Jennifer Doudna, who along with Emmanuelle Charpentier, created CRISPR Cas9, a powerful DNA genome-editing technology. It can be used to genetically engineer all forms of life, as we know it, by DNA manipulation, changing the sequence of genome & altering their patterns with what the editor desires. It is not the first time human ingenuity has created something capable of doing us great good and major harm. Are we up to the challenge of how CRISPR will & has shaped the future? Listen to Troof Revealed explain what we've been saying for years about this technology now! Pay close attention beloved & take heed! Amen ❤️ Donations welcome & much appreciated, Cash App: $MikiBlik --- Support this podcast: https://podcasters.spotify.com/pod/show/miki-blik/support

In this episode from the archives, originally published in February 2021, Jennifer Doudna, who won the 2020 Nobel Prize for the co-discovery of CRISPR-Cas9 with Emmanuelle Charpentier, chats with Vijay Pande, general partner at a16z Bio + Health. Together, they discuss the future of biology, whether discovery itself can be engineered and industrialized, and how biology can shape our future. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Today's changing world faces continuous social, economic, and environmental challenges—from disease to natural disaster to war. The leaders stepping up to solve these issues possess deep ambition, vision, and skills to bring their ideas to life. In this episode, host Gautam Mukunda speaks with Jennifer Doudna, Ph.D., Professor of Chemistry and Molecular and Cell Biology at UC Berkeley and Nobel Prize Winner in Chemistry and Esther Duflo, Ph.D., Professor of Poverty Alleviation and Development Economics at MIT and Nobel Prize Winner in Economic Sciences. Together, they discuss how great leaders can pioneer breakthroughs and effectively enact change—from discovery to implementation. Resources: Poor Economics by Abhijit Banerjee and Esther Duflo Good Economics for Hard Times by Abhijit Banerjee and Esther Duflo "There are so many things I kind of wish I had known early in my career, but the big ones for me are, first and foremost, that each person is an individual and has their own sets of passions, strengths, weaknesses, desires." – Jennifer Doudna, Ph.D., Professor of Chemistry and Molecular and Cell Biology at UC Berkeley "Try to avoid micromanaging people. You get much more done if you can trust someone to run with it." - Esther Duflo, Ph.D., Professor of Poverty Alleviation and Development Economics at MIT Follow @GMukunda on Twitter or email us at WorldReimagined@nasdaq.com For more information on this episode's guest please visit: Nasdaq.com/world-reimagined-podcast

We are on summer break as we work to bring you another exciting season this fall. So, for the next few weeks we’re sharing some of our favorite sessions from the June 2021 BIO Digital. Today, check out our session Breaking Barriers in Science featuring Dr. Jennifer Doudna, Nobel Laureate and CRISPR Pioneer. This session is sponsored by Johnson & Johnson. Speakers: Seema Kumar , Vice President of Innovation, Global Health and Policy Communication Dr. Jennifer Doudna , Nobel Laureate and CRISPR Pioneer

Dr. Jennifer Doudna, 2020 Nobel Prize winner in Chemistry, on the genome editing technology known as CRISPR. Dr. Doudna details the various applications of CRISPR technology and the innovations that she hopes will make it a successful and affordable treatment for disease.

This episode is also available as a blog post: http://pharmaceuticalintelligence.com/2020/06/06/programming-life-an-interview-with-jennifer-doudna-by-michael-chui-a-partner-of-the-mckinsey-global-institute/

The Bio Revolution has the potential to transform our lives, and genome editing—the ability to change the DNA sequence in a targeted way using CRISPR-Cas9, is one of the key innovations that has sparked imaginations while also raising its fair share of controversy. What is the origin of this technique? How do we weigh the enormous benefits against the potential risks? And what is its role in solving the global coronavirus pandemic? As part of the McKinsey Global Institute’s research on the Bio Revolution, partner Michael Chui spoke with Jennifer Doudna, PhD, one of the scientists who discovered the genome-editing technique CRISPR-Cas9 and leading proponent of its responsible use. Jennifer is a professor of molecular and cell biology and chemistry at the University of California, Berkeley. The Doudna lab pursues a mechanistic understanding of fundamental biological processes involving RNA molecules. To read a transcript of this episode, visit: mck.co/3dEJWhJ To read more about the Bio Revolution, visit: mck.co/biorev See www.mckinsey.com/privacy-policy for privacy information

Designer babies? On this episode, Neil deGrasse Tyson and Chuck Nice sit down with biographer Walter Isaacson to explore Neil’s interview with Nobel Prize-winning biochemist, Jennifer Doudna, about her pioneering work with CRISPR technology. NOTE: StarTalk+ Patrons can watch or listen to this entire episode commercial-free here: https://www.startalkradio.net/show/the-code-of-life-and-crispr-with-jennifer-doudna-and-walter-isaacson/ Thanks to our Patrons Miguel Santana!!, Cristina Magistrali, Phillipe Dewindt, Toren Wallengren, Eric Huffman, Christopher Sukhanenya, Dmitry Pugachevich for supporting us this week. Image Credit: Tim Tim (VD fr), CC BY-SA 4.0, via Wikimedia Commons Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus .

“Diagnosis goes hand in hand with vaccination, and of course with therapies as well. What CRISPR is doing is providing for rapid turnaround testing at a lower cost and higher throughput than we've had with other technologies. We'll see that happening in various testing labs, certainly around the U.S. And the nice thing about that is it really does go hand in hand with these vaccines that are coming forward.” When Jennifer Doudna first spoke with Mike on the podcast four months ago, she was looking forward to her revolutionary CRISPR technology being applied to COVID diagnosis. Today, the Innovative Genomics Institute, which she founded, has tested more than 100,000 virus samples, including many in the underserved communities around UC Berkeley, her academic home. Another development since August: Dr. Doudna received the Nobel Prize in Chemistry for her game-changing co-discovery of CRISPR, which may one day help facilitate the elimination of genetic diseases. “We have the sequence of the entire human genome now,” she reminds Mike. “That's been available for the last two decades. And what hasn't been possible up until now is an easy way to manipulate the code. Allow scientists to make a change to an individual gene or to a set of genes to understand first of all, how they work, but also, really importantly, make changes that correct disease-causing mutations. And that's what CRISPR now enables.”

In the last few years, the term CRISPR has exploded on the global scene, and with it UC Berkeley professor Jennifer Doudna, one of the pioneers in the field, has emerged into the spotlight. From magazine covers, to news broadcasts, to social media, CRISPR is the rare scientific breakthrough that has captivated the interest of the general public. But what is CRISPR really? What are its implications now and into the future? What profound ethical questions are raised by this ability to so precisely and easily edit the genome? In a candid and far-ranging conversation with Dan Rather, Doudna leads viewers through a nuanced and captivating view of this new technology. And along the way she shares her own improbable journey into science and her lessons for others – especially young women – who want to follow in her footsteps.Funding for this interview was provided by the Lasker Foundation.

“I really want to be building on this technology here at Berkeley and making sure that we are creating a community of scientists that are doing two things: not only extending this extraordinary science and thinking about how to apply genome editing in ways that will have real impact on humanity; but also doing it with an eye towards social responsibility.” It used to be the stuff of science fiction: A scientist discovers a way to edit genetic sequences in humans and plant life, creating new opportunities to eliminate diseases and famine. Except in Jennifer Doudna’s case, the CRISPR-Cas9 technology she co-invented in 2012 has already produced real-life benefits – along with a scramble to translate the game-changing process into more treatments and cures. In the meantime, it has shown promise in the fight against COVID. “CRISPR proteins are quite useful for detection of viruses,” the Berkeley biochemistry professor tells Mike. “In fact, that's what they naturally do in bacteria. And not only that, they operate by a molecular mechanism that allows them to release a signal when they find their targets. So they can report on the presence of a virus in real time and with a visual signal in a way that I think could be a very powerful diagnostic tool in the near future.”

What is CRISPR-Cas9 and how does it work? How do we edit genes? Jennifer Doudna, biochemist at UC Berkeley, explains. The gene editing technique, created by UC Berkeley biochemist Jennifer Doudna and her colleague, Emmanuelle Charpentier, director of the Max Planck Institute of Infection Biology in Berlin, has taken the research and clinical communities by storm as an easy and cheap way to make precise changes in DNA in order to disable genes, correct genetic disorders or insert mutated genes into animals to create models of human disease. CRISPR-Cas9 is a hybrid of protein and RNA – the cousin to DNA – that functions as an efficient search-and-snip system in bacteria. It arose as a way to recognize and kill viruses, but Doudna and Charpentier realized that it could also work well in other cells, including humans, to facilitate genome editing. The Cas9 protein, obtained from the bacteria Streptococcus pyogenes, functions together with a “guide” RNA that targets a complementary 20-nucleotide stretch of DNA. Once the RNA identifies a sequence matching these nucleotides, Cas9 cuts the double-stranded DNA helix. Read more about CRISPR: http://news.berkeley.edu/2015/11/12/crispr-cas9-gene-editing-check-three-times-cut-once/ Video by Roxanne Makasdjian and Stephen McNally Cas9 Apo Structure image by Ben.lafrance CC BY-SA 4.0 https://commons.wikimedia.org/wiki/File:Cas9_Apo_Structure.png CRISPR animation provided by the Innovative Genomics Initiative http://www.berkeley.edu http://www.facebook.com/UCBerkeley http://twitter.com/UCBerkeley http://instagram.com/ucberkeleyofficial https://plus.google.com/+berkeley

Host Paul Laudicina interviews 2020 Nobel Prize winner Dr. Jennifer Doudna, a CRISPR pioneer who is doing new work to understand and slow the spread of COVID-19. They discuss the current science behind testing, treatment, and vaccine development for COVID-19 and the wider state of the global commitment to public health. Coronavirus: A World Transformed is produced by the Global Business Policy Council at Kearney, a think tank deciphering today's biggest changes and their effects on global business. Learn more at kearney.com/gbpc .

Jennifer Doudna, co-discoverer of CRISPR-Cas9 and winner of the 2022 Nobel Prize in Chemistry, discusses how genome editing with CRISPR technology is transforming biology. CRISPR-Cas9, an RNA-guided enzyme with remarkable abilities to recognize and cleave DNA, operates by mechanisms that both explain its biological function and provide insights into technology development. Doudna covers research into this amazing family of proteins: where they came from, how they work and how CAS-9-based technologies are revolutionizing research, biomedicine and agriculture. Series: "Frontiers of Knowledge" [Science] [Show ID: 35215]

Conversations host Harry Kreisler welcomes Professor Jennifer Doudna of UC Berkeley for a discussion of her intellectual odyssey that led to the discovery of CRISPR-Cas9, a revolutionary tool for gene editing. In the conversation, they explore the implications of CRISPR-Cas9 for agriculture, biotechnology and biomedicine. They also discuss how education and public advocacy can broaden insight into the ethical and policy dimensions of the biological revolution that is upon us. Doudna received the Nobel Prize in Chemistry in 2022. Series: "Conversations with History" [Humanities] [Science] [Show ID: 34595]