Aubrey de GreyEvery podcast appearance, updated as new ones drop

In this episode of The Talk Spot, we interview Dr. Aubrey de Grey --President and CSO at LEV Foundation. To visit Dr. Grey's work, go to https://www.levf.org/ To visit Dr. Grey's Twitter, click here https://x.com/aubreydegrey To contact Dr. Grey, contact aubrey@levf.org The Talk Spot is an interview-centric podcast. To visit our website: https://ucaststudios.com/ To visit other podcasts: https://podcasts.apple.com/us/podcast/u-cast-studios/id1448223064 To visit our LinkedIn: https://www.linkedin.com/company/u-cast-studios Song: "Orion Canyon" By Insect Surfers

In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity. Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging , and his work continues to shape the future of longevity science. Takeaways Combination therapies are crucial for understanding aging. Rejuvenation may be easier than slowing down aging. Stem cell therapies hold great promise for the future. The immune system plays a significant role in aging. Biological age testing can provide insights into health. Gene therapy is a promising avenue for longevity research. Lifestyle factors have limited impact on lifespan extension. Understanding the hallmarks of aging is essential for interventions. Preventative maintenance is key to longevity. The future of aging research is bright with new technologies. Chapters 00:00 Introduction to Longevity and Aging Research 02:50 Combination Therapies in Aging Research 05:57 The Hallmarks of Aging 09:12 Interventions for Rejuvenation 11:57 Stem Cell Therapies and Their Future 15:03 The Role of the Immune System in Aging 17:56 Insights on Aging and Rejuvenation 20:47 Biological Age Testing and Its Implications 24:01 The Future of Gene Therapy in Aging 26:49 Lifestyle Factors and Aging 30:04 Conclusion and Final Thoughts Learn more about Aubrey's work: https://www.levf.org Visit Kayla's website: KaylaBarnes.com

In this episode of the Smarter Not Harder Podcast, Dr. Aubrey de Grey discusses the latest advancements in anti-aging technologies, including senolytics, telomerase, parabiosis, and regulatory progress. Join us as we delve into: + The definition of aging and its processes according to Dr. Aubrey de Grey. + Recent developments in rejuvenation technologies and global regulatory changes. + Practical advice and the role of individuals in the fight against aging. This episode is for you if: - You're fascinated by breakthroughs in aging and healthspan extension. - You want to hear from Dr. Aubrey de Grey, a leading expert in the field of longevity, about the latest in age reversal science. - You're curious how new technologies like synolytics, parabiosis, and telomerase are evolving. - You seek insights on bridging the gap between metabolism and better health. You can also find this episode on… YouTube: https://youtu.be/Eahkiv8_OCU Find out more about Dr. Aubrey de Grey: Longevity Escape Velocity (LEV) Foundation: https://www.levf.org/ LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/ Twitter: https://x.com/aubreydegrey Learn more about Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

🧪 Today in our Lab 🥼 we are going to take a coffee ☕ with Aubrey De Grey Aubrey de Grey is a pioneer in the field of longevity research, renowned for his groundbreaking work on rejuvenation biotechnology. With his visionary insights and relentless pursuit of scientific breakthroughs, Aubrey has become a leading figure in the quest to extend human lifespan and healthspan. Join us as we dive deep into the fascinating world of longevity science with Aubrey de Grey. In this riveting episode, we'll explore the latest advancements in rejuvenation therapy, the future of ageing research, and the profound implications for human health and longevity. Whether you're a seasoned biohacker, a wellness enthusiast, or simply curious about the secrets to living longer and healthier, this episode is not to be missed! We'll dive deep on: Why Aubrey is not a piano player Definition of Ageing Preventitive Maintenance Hormesis The Survival of the Slowest Theory The "exercise paradox" Longevity Escape Velocity The most impactful intervention among nutrition, exercise sleep etc. Role of famine on survival Why calorie restriction has an "irritating detail" in it Calorie restriction mimetics and why rapamycin is an exception How NMN works for longevity Berberine C60 and olive oil Methylene Blue Resveratrol Water and Deuterium fatty acids The Longevity Summit Dublin and the Longevity declaration How to support Aubrey and his research New studies and progress And much, much more. We will talk about: #biohacking #longevity #antiaging #resveratrol #metformin #methylene blue #c60 #olive oil Episode Sponsored by ThinkFit https://thinkfit.app/ "Live Intentionally - Combine Productivity with Wellness for a Balanced, Meaningful Life." Hit LIKE and SUBSCRIBE to support this channel! 😌 Links Alchimista Podcast Smart Links Un Libro al Giorno ITA https://link.chtbl.com/1lag Sapessatelo ITA https://link.chtbl.com/sapessatelo Caffe' dell' Alchimista (ITA/ENG) https://link.chtbl.com/CDA Aubrey Links mentioned on the episode: https://www.linkedin.com/in/aubrey-de-grey-24260b/ https://www.levf.org/ https://viento.ai/ https://dublinlongevitydeclaration.org/ https://www.ted.com/speakers/aubrey_de_grey https://www.youtube.com/watch?v=pL3DW6-xzLc <a href="https://www.amazon.com/Ending-Aging-audiobook/dp/B01EBAP43C/ref=sr_1_1?crid=S24WGE4Z724L&dib=eyJ2IjoiMSJ9.kyhL528ZiaDkIYdLVM6nIygV51VaI92u4YBY6Ua9IHFRY4ez_gVo0y_q7WJrXkH6vQkgDQGMDwE8nr9H7z9u0Dax6--De19XXlZFLRiRjFf5g2cItv6FF6gcwhswq_MagjPL2Wpk8BXmfG2c4LoYsldUSalXQa-_GrotjlhqY5fJ6D9VI5ssRJi4GDC7qFznClJq0EyYTP8iNshHcogb8u02lhYgvPmDDF94rxp_6-c.xN1RZ7HY2tkwCxF6RL27KevnYrRCoVccdqPQ5Mi8sZg&dib_tag=se&keywords=aubrey+de+grey&qid=1715257702&sprefix=aubrey+de+grey%2Caps%2C267&sr=8-1" target="_blank" rel="noreferrer

Our topic in this episode is progress with ending aging. Our guest is the person who literally wrote the book on that subject, namely the book, “Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime”. He is Aubrey de Grey, who describes himself in his Twitter biography as “spearheading the global crusade to defeat aging”. In pursuit of that objective, Aubrey co-founded the Methuselah Foundation in 2003, the SENS Research Foundation in 2009, and the LEV Foundation, that is the Longevity Escape Velocity Foundation, in 2022, where he serves as President and Chief Science Officer. Full disclosure: David also has a role on the executive management team of LEV Foundation, but for this recording he was wearing his hat as co-host of the London Futurists Podcast. The conversation opens with this question: "When people are asked about ending aging, they often say the idea sounds nice, but they see no evidence for any actual progress toward ending aging in humans. They say that they’ve heard talk about that subject for years, or even decades, but wonder when all that talk is going to result in people actually living significantly longer. How do you respond?" Selected follow-ups: Aubrey de Grey on X (Twitter) The book Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime The Longevity Escape Velocity (LEV) Foundation The SENS paradigm for ending aging , contrasted with the "Hallmarks of Aging" - a 2023 article in Rejuvenation Research Progress reports from the current RMR project The plan for RMR 2 The RAID (Rodent Aging Interventions Database) analysis that guided the design of RMR 1 and 2 Longevity Summit Dublin (LSD): 13-16 June 2024 Unblocking the Brain’s Drains to Fight Alzheimer’s - Doug Ethell of Leucadia Therapeutics at LSD 2023 (explains the possible role of the cribriform plate) Targeting Telomeres to Clear Cancer – Vlad Vitoc of MAIA Biotechnology at LSD 2023 How to Run a Lifespan Study of 1,000 Mice - Danique Wortel of Ichor Life Sciences at LSD 2023 XPrize Healthspan The Dublin Longevity Declaration ("DLD") Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration C-Suite Perspectives Elevate how you lead with insight from today’s most influential executives. Listen on: Apple Podcasts Spotify

Send us Fan Mail Dialogues In Longevity - A discussion with Dr. Aubrey de Grey & Dr. Michael Rose about the past, present and future of longevity biotechnology Host - Ira S. Pastor Special thanks to longevity advocate Eric Schulke (https://ruliaderic.wordpress.com/) for helping to organize and coordinate the episode - Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation ( https://www.levf.org/ ), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease. Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation. Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of 'The Mitochondrial Free Radical Theory of Aging', 'Ending Aging', and a large number of academic papers. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide. Dr. Michael Rose, Ph.D. ( https://www.faculty.uci.edu/profile/?facultyId=5261 ) is the Director of the Network for Experimental Research on Evolution (NERE), and Professor in the Department of Ecology and Evolutionary Biology at the University of California, Irvine, where his main area of work over the years has been the evolution of aging. He received his PhD from the University of Sussex in 1978. In 1991, Dr. Rose published seminal work per his text 'Evolutionary Biology of Aging' exploring a view of the subject based on antagonistic pleiotropy, the hypothesis that aging is caused by genes that have two effects, one acting early in life and the other much later. The genes are favored by natural selection as a result of their early-life benefits, and the costs that accrue much later appear as incidental side-effects that we identify as aging. Dr. Rose’s laboratory has conducted the longest-running artificial selection experiment designed to test the theory of antagonistic pleiotropy using Fruit flies (Drosophila melanogaster) bred for longevity by collecting eggs from the longest-lived flies in each generation. The experiment has run since 1981, and has produced flies with quadruple the original life span. In 1997, Dr. Rose was awarded the Busse Research Prize by the World Congress of Gerontology. He has authored 10 books, including 'The Long Tomorrow: How Advances in Evolutionary Biology Can Help Us Postpone Aging'. Support the show

How compatible are two very different giants in the longevity movement? Aubrey de Grey, the iconic and highly academically decorated bioscientist, paved the way for the early stages of scientific development, and Bryan Johnson, the software mogul turned one-man experiment and chief meme officer of longevity, focuses on the intersection of lifestyle and research. Do their very different approaches go together? They do! Let’s explore how they overlap with each other and how they are giving shape to the longevity movement. They navigate the intricate landscape of scientific advancement, with Aubrey opening the area of possibility through scientific progress and Bryan developing broader accessibility of solutions. Advancing From Early Stage Discovery In society, when someone demonstrates what's possible, it inspires others to follow suit. “My goal is to shift the current trend from being offensive, weird, and eccentric to being amazing through Blueprint.” – Bryan Johnson Change is inevitable because humans tend to doubt new technologies initially, but once they're available and add value to people’s lives, adoption grows, and it becomes the new normal. This is a recurring pattern in history; therefore, we should question our initial skepticism. Collaborations With The Traditional Clinical Sides Working together with clinicians is crucial. PhDs and MDs have different approaches, but they both understand the end goal: reducing human suffering. The process from lab to clinic is rocky and time-consuming, but there are pathways to streamline and accelerate. Although people like Bryan Johnson play a significant role in advancing the mainstream medical profession, they intelligently contribute by collecting relevant data to expedite the process of ensuring the safety and effectiveness of medical innovations, making them accessible to a wider audience beyond just the early adopters. Why Hasn't There Been A Moonshot For Longevity Yet? Traditionally, the Far East has been slower to embrace longevity research despite factors like respect for the elderly, demographic challenges, and technological prowess. Recently, this mindset might be changing, and if so, it could pave the way for a significant initiative akin to the Apollo project. One hurdle in the West is the centralization of science funding. Public officials act based on a desire for re-election and public opinion, but the public has a presumption against new technology. The solution could be more independent science funding, such as VitaDAO, and more “direct democracy,” such as citizen science. Aubrey's innovation and Bryan's practical focus signify the diverse strategies required for advancement, emphasizing the integration of discovery, clinical application, and societal acceptance of mainstream longevity technologies. Despite cultural and political challenges, this fireside chat underscores the potential for transformative initiatives and the necessity of collective action in propelling the longevity movement forward. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

"A large part of it is simply learned helplessness, as in like, we've been terribly aware of aging since the beginning of civilization and we have been completely unable to do anything about it. So we have simply developed these ways to put it out of our minds and get on with our miserably short lives and made the best of it, rather than being preoccupied with this terrible thing that's going to happen to us." On this episode of HYPERSCALE, I am joined by Aubrey de Grey, a world-famous transhumanist, writer, and biomedical gerontologist who has been researching the medical answer to aging in humans for over 30 years. He currently serves as President and Chief Science Officer at Longevity Escape Velocity Foundation. Aubrey notes that now that we have an actual plan to address aging, through tangible, tested medical science, we can begin to tackle and hopefully erode this entrenched learned helplessness surrounding the supposed inevitability of aging. After all, he believes that almost every aspect and side effect of aging is replicated in a kind of sped-up manner in certain diseases. Fortunately, there's been more funding in longevity research now than there was even five years ago. However, Aubrey notes that this funding is extremely unevenly distributed, where an overwhelming majority of it is going to a few "fashionable, let's call them low hanging areas, areas where progress has been made rapidly and where there's a good chance of making revenue fairly soon," he explains. "Because this is coming from investors more than from donors." Still, the fact that there is a greater number of people that are interested in longevity and the future of the human body bodes well for a future free of death. Ultimately, he emphasized, it's absolutely critical to understand that the idea of bringing aging under comprehensive medical control is "very much science foreseeable now, not science fiction." Join us in this exciting conversation as we hear from one of the greatest minds in the field of transhumanism, and what his vision for the future is like. FOLLOW ► Instagram: https://bit.ly/briarig LinkedIn: https://bit.ly/briarlinkedin TikTok: https://bit.ly/briartiktok WEBSITE: https://briarprestidgeofficial.com

Dr. Aubrey De Grey, a distinguished biomedical gerontologist, is a visionary in the field of aging research. His groundbreaking work has focused on finding ways to slow, prevent, and even reverse the aging process in humans and animals. As the founder of the SENS Research Foundation, Dr. De Grey has played a pivotal role in advancing the field of gerontology and biogerontology. With his unique background and revolutionary approach to aging, Dr. Aubrey De Grey has upended conventional wisdom, sparking both intrigue and controversy as he seeks to extend healthy human life. But what will be the implications of his discoveries? Dr. De Grey's passion for exploring the possibilities of ageless living has led him to challenge conventional wisdom and inspire countless gerontologists to rethink their approach to aging. Look into the Strategies for Engineered Negligible Senescence (SENS) Foundation, founded by Dr. Aubrey De Grey, to learn more about their research and approach to combating aging and age-related diseases. Explore the concept of Longevity Escape Velocity, which Dr. De Grey has proposed as a way to stay one step ahead of the aging process through repeated application of damage repair therapies. Familiarize yourself with the history of science and the paradigm shifts that have occurred throughout time, as this can help provide context for understanding the resistance Dr. De Grey faced in proposing his ideas on aging. Research the different types of age-related damage and their potential impact on health, including Alzheimer's disease, cancer, arthritis, and sarcopenia, to understand the importance of focusing on health span rather than just life span. Consider the analogy between living organisms and manmade machines, as proposed by Dr. De Grey, to better understand the concept of damage accumulation and the potential for repair in both living and non-living systems. Investigate the concept of negligible senescence as coined by Caleb Finch and how this idea has influenced Dr. De Grey's approach to engineered negligible senescence. Look for opportunities to engage with the gerontology community and participate in discussions surrounding the potential for extending health spans and combating age-related diseases. Engineered Negligible Senescence Engineered Negligible Senescence (ENS) seeks to prevent or reverse the aging process, focusing on the repair of cellular and molecular damage that accrues over time. The underlying principle is that our biological age, determined by the wear and tear our bodies undergo, can be slowed down and potentially extended through vigilant maintenance. The ultimate goal of ENS is not simply to prolong life for its own sake, but to increase health span, curtailing age-related illnesses such as Alzheimer's, cancer, sarcopenia, and arthritis. Dr. Aubrey De Grey, a guest on the Beauty and the BS with Dr. Peter Grossman podcast, elaborated on the concept of ENS and its importance in addressing age-related health problems. Although his ideas faced resistance initially, De Grey remains confident in their potential benefits within his lifetime. By focusing on periodic, preventative maintenance, he believes it may be possible to delay the issues related to aging by 20 or 30 years, ultimately leading to longer, healthier lives. About the Host, Dr. Peter Grossman: https://grossmanmed.com/about Podcast Page: www.beautyandthebspodcast.com

With his unique background and revolutionary approach to aging, Dr. Aubrey De Grey has upended conventional wisdom, sparking both intrigue and controversy as he seeks to extend healthy human life. But what will be the implications of his discoveries? In this episode of Beauty and the BS with Dr. Peter Grossman, you will be able to: 1. Discover the significance of gerontology and biogerontology in addressing the aging process. 2. Understand engineered negligible senescence and its role in comprehensive periodic maintenance. 3. Explore how repairing molecular and cellular damage can counteract aging. 4. Learn about the potential of stem cell therapy as a cutting-edge damage repair strategy. 5. Delve into the controversy surrounding prolonged human life and the benefits it may hold. Dr. Aubrey De Grey, a distinguished biomedical gerontologist, is a visionary in the field of aging research. His groundbreaking work has focused on finding ways to slow, prevent, and even reverse the aging process in humans and animals. As the founder of the SENS Research Foundation, Dr. De Grey has played a pivotal role in advancing the field of gerontology and biogerontology. With a keen understanding of the complex interplay between molecular and cellular damage, he has developed innovative strategies for promoting healthier, longer lives. Dr. De Grey's passion for exploring the possibilities of ageless living has led him to challenge conventional wisdom and inspire countless gerontologists to rethink their approach to aging. The key moments in this episode are: 00:00:08 - Introduction to Gerontology and Biomedical Gerontology 00:02:13 - Chronological Age versus Biological Age 00:05:03 - Aging and Damage Accumulation 00:11:20 - Engineered Negligible Senescence 00:16:50 - Postponing Aging to Battle Health Issues 00:17:58 - Life Expectancy vs. Lifespan 00:21:17 - Longevity and the Controversy 00:24:02 - Categorizing Aging Damage 00:25:12 - Cell Loss and Stem Cell Therapy 00:27:05 - The Importance of Classification The resources mentioned in this episode are: Look into the Strategies for Engineered Negligible Senescence (SENS) Foundation, founded by Dr. Aubrey De Grey, to learn more about their research and approach to combating aging and age-related diseases. Explore the concept of Longevity Escape Velocity, which Dr. De Grey has proposed as a way to stay one step ahead of the aging process through repeated application of damage repair therapies. Familiarize yourself with the history of science and the paradigm shifts that have occurred throughout time, as this can help provide context for understanding the resistance Dr. De Grey faced in proposing his ideas on aging. Research the different types of age-related damage and their potential impact on health, including Alzheimer's disease, cancer, arthritis, and sarcopenia, to understand the importance of focusing on health span rather than just life span. Consider the analogy between living organisms and manmade machines, as proposed by Dr. De Grey, to better understand the concept of damage accumulation and the potential for repair in both living and non-living systems. Investigate the concept of negligible senescence as coined by Caleb Finch and how this idea has influenced Dr. De Grey's approach to engineered negligible senescence. Look for opportunities to engage with the gerontology community and participate in discussions surrounding the potential for extending health spans and combating age-related diseases. Engineered Negligible Senescence Engineered Negligible Senescence (ENS) seeks to prevent or reverse the aging process, focusing on the repair of cellular and molecular damage t

“Ageing is, simply and clearly, the accumulation of damage in the body. That’s all that ageing is.–Aubrey de Grey www.savagechickens.com " data-medium-file="https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg?w=162" data-large-file="https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg?w=400" src="https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg" alt="" class="wp-image-5106" width="203" height="376" srcset="https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg?w=203&h=376 203w, https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg?w=81&h=150 81w, https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg?w=162&h=300 162w, https://seekingdelphidotcom.files.wordpress.com/2020/11/fact-science.jpg 400w" sizes="(max-width: 203px) 100vw, 203px" /> http://www.savagechickens.com It’s that simple. Or so say Aubrey de Grey and his many followers in the gerontological and biotech communities. But the sixty-four dollar question is: how does the message disseminate to the rest of the world? Regulators…legislators…the public at large…they all need to understand the viability of this research, and the very real benefits that humanity could gain if it succeeds. No, it’s not there yet, and no, there are no guarantees that it will ever get there. But the probability of success grows with every passing breakthrough, day by day. In this episode of The Longevity Dialogues on Seeking Delphi, we discuss the ins and outs of Selling the Science. The panelists: Aubrey de Grey– chief science officer of the SENS research foundation and author of Ending Aging . Nir Barzilai, MD- founding director of the Institute for Aging Research, at Albert Einstein College of Medicine of Yeshiva University. Author of Age Later. Keith Comito– Founder and president of the Life Extension Advocacy Foundation. You can subscribe to Seeking Delphi on Apple podcasts , PlayerFM, MyTuner, Listen Notes , and YouTube. You can also follow us on twitter @Seeking_Delphi and <a rel="noreferrer noopener" href="https://www.facebook.com/seekingdelphi/" target="_b

Aubrey de Grey , Chief Science Officer at SENS Research Foundation , explores the concept of using biomedical technology and regenerative medicine to postpone aging-derived debilitation and death. We dive into many questions surrounding this topic, including the benefits of reversing aging/age-related disease vs. slowing it down and the potential ethical or medical concerns around extending life beyond what is “natural.” To find out more about Impetus: https://www.meetwithimpetus.com Natalie Yeadon LinkedIn: https://www.linkedin.com/in/natalieyeadon/ Impetus Digital Website: https://www.impetusdigital.com/ Impetus Digital LinkedIn: https://www.linkedin.com/company/impetus-digital/ Impetus Digital Twitter: https://twitter.com/impetus_digital Impetus YouTube: https://www.youtube.com/ImpetusDigital Aubrey de Grey: https://www.linkedin.com/in/aubrey-de-grey-24260b/ SENS Research Foundation: https://www.sens.org/ Impetus Digital has been delivering best-in-class virtual and hybrid meetings, events, and programs for global life science companies since 2008. We work closely with clinical, market access, medical affairs, marketing, medical education, and many other departments to virtualize their internal and external stakeholder meetings, such as advisory boards, learning programs, working groups, and congress engagement initiatives. We partner with clients at all stages of the product life cycle, from R&D to loss of exclusivity. Click the social media buttons to share this episode with your network! To learn more about Impetus, our services, and our tools: https://www.meetwithimpetus.com Natalie Yeadon LinkedIn: https://www.linkedin.com/in/natalieyeadon/ Impetus Digital Website: Home Page LinkedIn: https://www.linkedin.com/company/impetus-digital/ Twitter: impetus_digital YouTube: Impetus Digital

Scientists who study the biology of Aging agreed that we would someday be able to slow down the aging process substantially. Dr. Aubrey de Grey, Chief Science Officer at SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, believes that the critical biomedical technology required to eliminate aging derived debilitation and death is now within reach. In his book “Ending Aging” he and his research assistant Michael Rae described the details of this biotechnology. They explained that the aging of the human body, just like the Aging of manmade machines, results from an accumulation of various types of damage. As with manmade machines, this damage can periodically be repaired, leading to the indefinite extension of the machines fully functional lifetime just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging, Dr. Aubrey de Grey systematically dismantles the fatalist presumption that aging will forever defeat the efforts of medical science. He is the author of “Ending Aging,” rejuvenation breakthroughs that could reverse human Aging in our lifetime. His book is available at Amazon.com: https://www.amazon.com/Ending-Aging-Rejuvenation-Breakthroughs-Lifetime/dp/B01EBAP43C/ref=sr_1_1?keywords=Ending+Aging+aubrey+de+grey&qid=1583555592&sr=8-1 Aubrey's Links: LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/ Personal Website: https://www.sens.org/ Company Website: https://www.mfoundation.org/ Twitter: https://twitter.com/aubreydegrey This podcast is also available on Podcast.BoomerLiving.tv at the link: https://podcast.boomerliving.tv/ending-aging-by-reversing-human-aging-in-our-lifetime-with-dr-aubrey-de-grey-phd/

This episode will take you through Dr. Aubrey de Grey’s Seven Pillars of aging, the research that he's currently doing, his opinion on biological age, AGEs and the different sources, and the impact of growth hormone on biological age. Who is Dr. Aubrey de Grey? Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc. He is the editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem. His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies. He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. He is also a member of Flooved advisory board. Highlights [1:57] Where are we in the battle against aging? [4:29] Dr. de Grey explains the seven aspects of aging [8:38] Effects of lifestyle on the AGEs and aging [12:23] Measures for biological age [18:07] Why haven’t we evolved past aging? [20:28] Alzheimers, cancer and cardiovascular disease as components of aging [24:44] Transitioning from computer science to gerontology [27:53] Dr. de Grey answers the Superhuman six Resources The Health Optimisation Summit Horvath’s Epigenetic clock Reversing Biological Age by Greg Fahy Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Our sponsor today is CAR.O.L You don’t have time for that 45 minute jog. You need something fast, efficient, and leaves you wanting more. My favorite tool for this is the CAR.O.L. She is a life-changing bike, that provides you all the endurance you need into two 20 second bursts. Yes, you read that right. That’s 40 seconds of max-effort, including the warm up and cool downs, you get a kick-ass workout in 8 minutes and 40 seconds. The CAR.O.L is a resistance bike powered by artificial intelligence, which personalizes and optimizes the resistance, so you hit your maximum intensity levels and maximize glycogen depletion every single time. The proof is really in the pudding. CAR.O.L’s effectiveness was independently verified by the American Council on Exercise. I gave the CAR.O.L bike spin at Health Optimization Summit in London this year, and she kicked my ass so much that I had to get one. <

Today's Flash Back Friday comes from Episode 106, originally published in September 2012. Dr. Aubrey de Grey, a biomedical gerontologist, joins Jason Hartman on this episode to discuss how close we're getting to finding the proverbial Fountain of Youth. Dr. de Grey explains that the aging process is simply the collection of early stages of the illusion of old age, i.e. cell damage and loss. He said the accumulation of aging side effects leads to the diseases and conditions of old age that we do not notice during younger ages. He describes the human body as a machine, albeit a very complicated and complex machine, and therefore, it should come as no surprise that the body breaks down over time. Dr. de Grey and the SENS Foundation have a plan to repair various areas of cell damage and cell loss through processes such as stem cell replacement therapies to slow the aging process. Dr. de Grey talks about the science, the research, the obstacles and the funding of this important work. He assures us that once this work is up and running, it will be the real deal allowing people to look and feel younger, but he stresses that this would be preventative care. Jason and Dr. de Grey also address the implications of slowing the aging process on the world population, the age to which people continue to work, pensions, and our carbon footprint. Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA, and is the Chief Science Officer of SENS Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. He received his BA and Ph.D. from the University of Cambridge in 1985 and 2000 respectively. His original field was computer science, and he did research in the private sector for six years in the area of software verification before switching to biogerontology in the mid-1990s. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism ("damage") that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence (SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one. A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels. Dr. de Grey has termed this required rate of improvement of repair therapies "longevity escape velocity". Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. Website: www.SENS.org

Dr. Aubrey de Grey is a biological gerontologist on a crusade to defeat aging. He thinks we are within a couple of decades of rejuvenation medicine capable of adding another 30 years to human lifespan, proposing that the first person to live to 1,000 years old may already be alive today. In the field of longevity science, there are a few roadblocks, but the biggest one is funding. They discuss why it isn't a higher priority for average people to further this research. Mark and Dr. de Grey cover a number of concepts at the forefront of anti-aging, such as whether increasing telomere lengths may be beneficial against aging or may cause side effects. Dr. de Grey suggests we learn more about the subject of defeating aging. Then become an advocate for the research, to bring about these medicines faster. Mark also asks Dr. de Grey about the morality of pursuing greater longevity for humans. Also on the podcast, Mark and Dr. Gladden discuss how the typical medical approach isn't designed to promote longevity but treat the immediate problem. Medicine is still, after all, a business. Reimbursement is always going to trump research. They consider de Grey's focus on finding a big breakthrough, versus the approach of making what you have better now, along the way. For more information on This Week in Longevity Science, visit https://news.osu.edu/news/2017/08/07/regenerative-med-study/ . Dr. Gladden expands on the function of stem cells in regard to these new findings. Ask yourself, "How does it change your thinking about the structure of your family, your work, community, etc., when you consider the ability to live 120 robust years?" About the guest: Dr. de Grey is the biomedical gerontologist who researched the idea for and founded SENS Research Foundation. Learn more at http://www.sens.org/ . He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research , is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. Follow de Grey on Twitter @AubreydeGrey and Facebook: https://www.facebook.com/drdegrey/ Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns

Alright everyone, here is Episode 62, “Forever Young” featuring Dr. Aubrey de Grey. This and all of our episodes are sponsored by Thermo-Fisher Scientific. Go to stemcellpodcast.com for all of our episodes and to sign up for our newsletter. We begin as always with the Science Round Up, sponsored by Biotechne and discuss the latest science/stem cell news including: differences in males and females stress susceptibility key elements of healthy eating habits a new marker of stem cells in the ovaries engineered stem cells may help in ALS how squeezing cells can help reprogramming efficiency For the interview portion of the show, sponsored by STEMCELL Technologies, we bring on writer, and researcher Dr. Aubrey de Grey to discuss his work on anti-aging. We talk with Dr. de Grey on his latest findings and his ultimate goal of eliminating aging so we call can one day celebrate our 1000th birthday. After this, there is a rant about how ridiculous cable bills are. This will be our last episode before we take a short break. Remember, during the break we will still do a science round up and some sort of interview feature that we will post online. Be sure to sign up for our newsletter at stemcellpodcast.com and follow us on twitter to find out: when the podcast will re-launch who the new hosts are where to access the science round up Talk to you SOON! Below are all of the papers mentioned on the show. We are working on a way to categorize all of the research papers we mention and possibly even provide audio summaries. Enter in your name and e-mail address below, and we will notify you of when this feature is available. Resources, Links and Research Papers Mentioned In This Session Include: Sex-Specific Mechanisms of Stress Susceptibility – According to this article, stress-related mental illnesses are twice as prevalent in women as in men. Global Divergence Of The Human Follicle Mite Demodex folliculorum: Persistent Associations Between Host Ancestry And Mite Lineages – In this article, researchers found that hosts with different regional ancestries harbor distinct lineages of mites and that these associations can persist despite generations spent in a new geographic region. Pain Produces Memory Gain – This article reveals that physical pain can make memories last longer. Integrated, Multi-cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses – In this article, researchers performed two integrated, multi-cohort analyses of publicly available transcriptional data of viral infections. Human Parasites in the Roman World – This article presents the archaeological evidence for parasites in the Roman era in order to demonstrate the species present at that time, and highlight the health consequences for people living under Roman rule.

There are those who would say that Aubrey de Grey is out to cure death, but what this former artificial intelligence specialist turned gerontologist is really focused on is health -- and the side effect of health is living a lot longer. In this segment of the a16z podcast we talk with Aubrey de Grey on the subject of aging and health, and how his training as a computer scientist helped him approach the problem in a different way from traditional biologists. The intersection of software and biology, and how this “troublemaker” from the computer science world is trying to keep us all healthy for a very, very long time. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Could you live to 1000? Would you want to? Today's Zestology podcast guest makes some extraordinary claims. Cambridge scientist and researcher Dr. Aubrey de Grey argues that aging is merely a disease and a curable one too. He talks about a post-ageing world. Humans age in seven basic ways, he says, all of which can be reversed, eventually. He is a celebrated and controversial scientist and researcher, and he says the first person to live to 1000 might be alive already. Amazing prospect. You could be 30,40,50 now and you could live to 150, or even 1000. Crazy, right? But that is what Aubrey De Grey is suggesting will happen. His popular TED talk on the subject has had hundreds of thousands of views. He is definitely a maverick and controversial, and this is a must-listen Zestology. When you listen you'll hear: Living with more energy What does a post-aging society look like? [4:20] Stem cells as a way to treat Parkinson’s disease [8:10] Improving people’s quality and quantity of life [14:20] What to look forward to in 20/25 years [24:00] Finding a mission in life [25:50] Easy, everyday tips for vitality Reverse aging therapy [7:20] Performing mentally and physically like a young adult… again [9:50] Eliminating illness (Can we do it?) [18:45] A war on aging [21:43] Finding motivation Do we want extreme longevity? [2:45] Could you work until you’re 150? [16:05] When will we live to 1000? [13:10] How to live to 1000 (in one easy step) [23:10] JOIN the Zestology MAILING LIST by going to our website (<a href="http://

Cast : Rob, Mike, and Aubrey de Grey Topics : A Conversation with Aubrey de Grey BS! Sponsors : Meta-Games Unlimited and Obsidian Portal BS! Memberships : Spooky Outhouse Productions Music : All music used with permission of Ghoultown Songs Used: Under a Phantom Moon, Killer in Texas, and Train to Nowhere See Aubrey’s work here.